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IRCT20130812014333N169 IRCT 2021-06-07 Kermanshah University of Medical Sciences Comparison of extracorporeal shock wave therapy with Intra-Plaque Injection of Verapamil in the Treatment of Peyronie's Disease Comparative study of extracorporeal shock wave therapy (ESWT) and Intra-Plaque Injection of Verapamil in the Treatment of Peyronie's Disease 2021-06-04 anticipated 34 Complete https://irct.ir/trial/56226 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Using the random number table, patients are divided into two groups. Each patient is assigned a 4-digit code based on the random number table, Based on the right number of patients code, the patients are divided into two groups. Patients whose last digit is 0, 2, 4, 6, 8 will be assigned to the first intervention group and patients whose last digit is 1,3,5, 7, 9 will be second intervention group. 2-3 Peyronie's disease. Intervention 1: In the first intervention group, for patients, verapamil with a dose of 10 mg and diluted in 10 ml of distilled water using a 10 ml syringe and a needle with a 25 gauge will be injected intralesionally twice a week for 12 weeks. Intervention 2: In the second intervention group, patients will receive extracorporeal shock wave therapy in the form of 2000 shocks per session with an energy of 0.29 millijoules per square meter using a program of 1 session per week for 12 weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information
public Sajad Moradi
Emam Reza Hospital, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 sajad3258985952@gmail.com Kermanshah University of Medical Sciences scientific Dr. Hossein Abdi
Emam Reza Hospital, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 abdihossein96@yahoo.com Kermanshah University of Medical Sciences Iran (Islamic Republic of) Age between 18 and 65 The duration of the disease is more than 12 months Diagnosis of pneumonia based on the opinion of a urologist and the presence of palpable plaque Married patients 18 years 65 years Both Patient with calcified plaque History of penile surgery History of hypo or epispadias History of intra-plaque injection into the penis Existence of 2 lesions or lesions with non-measurable shape N48.6 Induration penis plastica Treatment - Drugs Treatment - Other In the first intervention group, for patients, verapamil with a dose of 10 mg and diluted in 10 ml of distilled water using a 10 ml syringe and a needle with a 25 gauge will be injected intralesionally twice a week for 12 weeks. In the second intervention group, patients will receive extracorporeal shock wave therapy in the form of 2000 shocks per session with an energy of 0.29 millijoules per square meter using a program of 1 session per week for 12 weeks. The amount of pain. Timepoint: Beginning of study, end of week 16. Method of measurement: Based on Visual Pain Scale (VAS). Erectile dysfunction. Timepoint: Beginning of study, end of week 16. Method of measurement: Based on the Erection Function Questionnaire. Kermanshah University of Medical Sciences Approved 2021-04-26 Ethics committee of Kermanshah University of Medical Sciences Vice Chancellor for Research Affairs, Building No.2, Shahid Beheshti, Kermanshah University of Medical Sciences Kermanshah Kermanshah Iran (Islamic Republic of)