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IRCT20200127046282N12 IRCT 2022-05-01 Tehran University of Medical Sciences PRP Versus Tranexamic Acid mesoneedling in Melasma Treatment Platelet Rich Plasma Versus Tranexamic Acid mesoneedling in Melasma Treatment: A Split Face Comparative Study 2022-04-19 anticipated 45 Complete https://irct.ir/trial/56346 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Blinding description: In each session, one group receives PRP along with microneedling and the other group receives PR with microneedling. Only the he data analyzer will not have information from the intervention groups. 1 Melasma. Intervention 1: Intervention group: At each session, the right side of the patient's face receives PRP along with microneedling. Intervention 2: Control group: At each session, the left side of the patient's face receives ohs with microneedling. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is -
public Sona Zare
No 4, Maryam Alley, South Kamraniyeh Street, Tehran
Tehran Iran (Islamic Republic of) 1937957511 +98 21 2665 7438 sonazarebio@gmail.com Skin and stem Cell Research Center, Tehran University of Medical Sciences scientific ‪Masoumeh Roohaninasab
No 4, Maryam Alley, South Kamraniyeh Street, Tehran
Tehran Iran (Islamic Republic of) 1937957511 +98 21 2221 5558 masoomehrohani@yahoo.com Skin and Stem Cell Research Center, Tehran University of Medical Sciences Iran (Islamic Republic of) People with melasma on the cheeks and other areas of the face no limit no limit Both Any complication that is related to the treatment process or is not tolerated by the patient The patient does not want to continue treatment for any reason Cancers, pregnancy, lactation, DVT, pulmonary embolism, stroke Incidence of drug allergies Occurrence of hypertrophic or colloidal scars at the treatment site L81 Other disorders of pigmentation Treatment - Other Treatment - Other Intervention group: At each session, the right side of the patient's face receives PRP along with microneedling. Control group: At each session, the left side of the patient's face receives ohs with microneedling. Melasma area recovery rate. Timepoint: Before treatment and 1 month after the last session. Method of measurement: Visioface. Side effects. Timepoint: One week after session. Method of measurement: Questionnaire and visit. Satisfaction. Timepoint: 1 months after the last session. Method of measurement: Questionnaire and visit. Tehran University of Medical Sciences Approved 2021-04-07 Ethics Committee of Tehran University of Medical Sciences Tehran University of Medical Sciences, Keshavarz blvd. Tehran Tehran Iran (Islamic Republic of)