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IRCT20210525051394N1 IRCT 2021-06-10 Mashhad University of Medical Sciences Comparison of the effect of Isoflurane and Propofol on prevention of emergence agitation in children Comparison of the effect of Isoflurane and Propofol on prevention of emergence agitation in children under 3 having probing surgery 2021-06-06 anticipated 108 Complete https://irct.ir/trial/56518 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: The blocking method is divided into two groups using the sealedenvelop.com website, Blinding description: .The method of concealment will be to use sealed, opaque envelopes . Due to the fact that patients are anesthetized, they are unaware of the type of medicine used and have been blinded. The data analyst is also unaware of the assigned groups at the time of analysis. 3 agitation. Intervention 1: Intervention group: Maintenance Anesthesia with hypnotic intravenous drug ( propofol) at a dose of 50 to 100 μg / kg at interoperation time. Intervention 2: Control group: Maintenance Anesthesia with inhalathion anesthetic ( isoflurane)2.5% at interoperation time. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is not necessary
public Hamideh Zarezadeh
No.55,Ordibehesht Ave,seyed mortazaBlv
Kashmar Iran (Islamic Republic of) 9671983957 +98 51 5525 4480 zarezadehh971@mums.ac.ir Mashhad University of Medical Sciences scientific Hamideh Zarezadeh
NO .55 .Aveordibehesht.Blvd seyed morteza
Kashmar Iran (Islamic Republic of) 9671983957 +98 51 5525 4480 zarezadehh971@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) All children under three years old referred to Khatam Al-Anbia Hospital in Mashhad having probing surgery 30 days 3 years Both Children with underlying psychiatric disorder Children with underlying disease Convulsions Dissatisfaction of parents Drug allergy R45.1 Restlessness and agitation Prevention Prevention Intervention group: Maintenance Anesthesia with hypnotic intravenous drug ( propofol) at a dose of 50 to 100 μg / kg at interoperation time Control group: Maintenance Anesthesia with inhalathion anesthetic ( isoflurane)2.5% at interoperation time Severity of agitation. Timepoint: preoprative child evaluathion,postoperative and recavery child severity agitathion evaluathion. Method of measurement: Richmond Sedation-Agitation Scale. Mashhad University of Medical Sciences Approved 2021-05-30 Ethics committee of Mashhad university of medical sciences Medical school, Mashhad university of medical sciences, Azadi sq. Mashhad Razavi Khorasan Iran (Islamic Republic of)