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IRCT20161019030377N1 IRCT 2021-12-18 Sanandaj University of Medical Sciences Comparative study of effect of three mouthwashes Listerine, Irsha, and Vi one general on the salivary streptococcus mutans level. Comparative study of effect of three mouthwashes Listerine, Irsha, and Vi one general on the salivary streptococcus mutans level. 2021-06-05 anticipated 90 Complete https://irct.ir/trial/56574 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: For the first time, the clinical efficacy of Vi One mouthwash in relation to other mouthwashes in reducing salivary streptococcus mutans is being evaluated, Randomization description: The names of all the people who are eligible to enter the research (180 people) are written on separate cards and all are placed in a container, then the people who are drawn out one by one, The research samples (90 people) are randomly divided into three groups of one, two and three. They are written with the letter A, another third with the letter B, and the other third with the letter C, and people are grouped into one, two, or three based on the letter of the selected card, Blinding description: The present study will be single blinded and all mouthwashes are prepared into opaque bottles of the same volume without any specifications. N/A salivary streptococcus mutans. Intervention 1: Intervention group: Listeine mouthwash:Samples are asked to use this mouthwash once a day for 2 weeks and after using the mouthwash, avoid consuming any food and drink for at least 30 minutes and also to rinse the mouth. Before and after using the mouthwash, saliva sampling is performed from all participants. In this way,They are asked to rinse their mouths with saline before eating breakfast and brushing their teeth, and to rinse their contents after rinsing. 1 cc of their non-stimulated saliva is then collected by spitting into a sterile tube and immediately sent to a laboratory for microbial culture and measurement of Streptococcus mutans (CFU / ml). Intervention 2: Intervention group: Vi One general mouthwash :Samples are asked to use this mouthwash once a day for 2 weeks and after using the mouthwash, avoid consuming any food and drink for at least 30 minutes and also to rinse the mouth. Before and after using the mouthwash, saliva sampling is performed from all participants. In this way,They are asked to rinse their mouths with saline before eating breakfast and brushing their teeth, and to rinse their contents after rinsing. 1 cc of their non-stimulated saliva is then collected by spitting into a sterile tube and immediately sent to a laboratory for microbial culture and measurement of Streptococcus mutans (CFU / ml). Intervention 3: Intervention group: Irsha mouthwash:Samples are asked to use this mouthwash once a day for 2 weeks and after using the mouthwash, avoid consuming any food and drink for at least 30 minutes and also to rinse the mouth. Before and after using the mouthwash, saliva sampling is performed from all participants. In this way,They are asked to rinse their mouths with saline before eating breakfast and brushing their teeth, and to rinse their contents after rinsing. 1 cc of their non-stimulated saliva is then collected by spitting into a sterile tube and immediately sent to a laboratory for microbial culture and measurement of Streptococcus mutans (CFU / ml). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is no more information
public Seyyedeh Pouya Morovati
Pasdaran Street
Sanandaj Iran (Islamic Republic of) 66177713446 +98 87 3366 8770 pouyamorovati@gmail.com Sanandaj University of Medical Sciences scientific Seyyedeh Pouya Morovati
Pasdaran Street
Sanandaj Iran (Islamic Republic of) 66177713446 +98 87 3366 8770 pouyamorovati@gmail.com Sanandaj University of Medical Sciences Iran (Islamic Republic of) Dental Students of Kurdistan University of Medical Sciences Informed Consent 18 years no limit Both antibiotic consumption within recent month fluoride therapy within recent month orthodontic appliance immune- compromised condition like Diabetic patients soft tissue oral pathology like PGCG etc. K02 Dental caries Prevention Prevention Prevention Intervention group: Listeine mouthwash:Samples are asked to use this mouthwash once a day for 2 weeks and after using the mouthwash, avoid consuming any food and drink for at least 30 minutes and also to rinse the mouth. Before and after using the mouthwash, saliva sampling is performed from all participants. In this way,They are asked to rinse their mouths with saline before eating breakfast and brushing their teeth, and to rinse their contents after rinsing. 1 cc of their non-stimulated saliva is then collected by spitting into a sterile tube and immediately sent to a laboratory for microbial culture and measurement of Streptococcus mutans (CFU / ml). Intervention group: Vi One general mouthwash :Samples are asked to use this mouthwash once a day for 2 weeks and after using the mouthwash, avoid consuming any food and drink for at least 30 minutes and also to rinse the mouth. Before and after using the mouthwash, saliva sampling is performed from all participants. In this way,They are asked to rinse their mouths with saline before eating breakfast and brushing their teeth, and to rinse their contents after rinsing. 1 cc of their non-stimulated saliva is then collected by spitting into a sterile tube and immediately sent to a laboratory for microbial culture and measurement of Streptococcus mutans (CFU / ml). Intervention group: Irsha mouthwash:Samples are asked to use this mouthwash once a day for 2 weeks and after using the mouthwash, avoid consuming any food and drink for at least 30 minutes and also to rinse the mouth. Before and after using the mouthwash, saliva sampling is performed from all participants. In this way,They are asked to rinse their mouths with saline before eating breakfast and brushing their teeth, and to rinse their contents after rinsing. 1 cc of their non-stimulated saliva is then collected by spitting into a sterile tube and immediately sent to a laboratory for microbial culture and measurement of Streptococcus mutans (CFU / ml). Reduction of salivary streptococcus mutans. Timepoint: 2weeks. Method of measurement: Samples are asked to use mouthwash once a day for 2 weeks and after consuming mouthwash for at least 30 minutes to refrain from consuming any food and beverages as well as mouth washing. Saliva samples are taken from all participants before and after mouthwash. The sampling method is to ask them to rinse their mouths with saline before eating breakfast and brushing their teeth. Then 1 cc of non-stimulating saliva is collected by spitting in a sterile tube and immediately sent to the laboratory for microbial culture and measurement of Streptococcus mutans (CFU / ml). Sanandaj University of Medical Sciences Approved 2021-01-11 Ethics committee of Kurdistan University of Medical Sciences Pasdaran Street Sanandaj Kurdistan Iran (Islamic Republic of)