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IRCT20210608051514N1 IRCT 2021-06-20 Zanjan University of Medical Sciences treatment schizophrenia patients: double-blind randomized controlled trial Title: The Effectiveness of tDCS over the DLPFC on reducing clinical symptomsimproving working memory and aberrant EEG functional connectivity in resting state schizophrenia patients: double-blind randomized controlled trial 2021-07-23 anticipated 30 Complete https://irct.ir/trial/56739 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Subjects are selected from purposive sampling method and using simple randomization method, based on which the subjects are assigned to the two groups of control and experiment by tossing coins.This method is used for two-group clinical trials, according to which one group is called a lion, and the other is called a line, and thus the number of coin samples is tossed, Blinding description: In this study, the clinical evaluator and therapist will be blind to assigning subjects to control and experimental groups. In addition, we use the clinical evaluator separately for baseline assessments and follow-up, and the therapist separately for treatment.Subjects will also be assigned to control groups or blind experiments, so that subjects will not meet outside of the sessions and will visit at times when no other subjects will be present. N/A schizophrenia. Intervention 1: Intervention group: Treatment with stimulation of extracranial direct current with a current of 2 mA for 20 minutes on the lateral dorsal forehead cortex will receive ten sessions for five days and two sessions a day. Intervention 2: Control group: Treatment with stimulation of extracranial direct current with a current intensity of two milliamperes for 40 seconds on the lateral dorsal forehead cortex will receive ten sessions for five days and two sessions daily. Yes - There is a plan to make this available What will be shared: All information of individuals except names and confidential information will be published at the end of the research. Publishable information including: therapeutic changes, results of questionnaires, statistical results of signal analysis, dose and medication used When: The results of this research will be published three months after the end of the research. To whom: All researchers, researchers, colleagues, and others Conditions: To carry out similar projects and if all the material and intellectual rights of researchers are observed. Where to obtain: Contact the following email address to receive the documentation: Farahnaz Yousefi Master of Clinical Psychology farahnaz.yosefi76@gmail.com Address: Department of Clinical Psychology and Psychiatry, Beheshti Hospital, Ark Gate, Chahar Ra Saadi, Zanjan Province How to obtain: The data will be provided to the applicant after receiving the e-mail of the applicant and observing the material and intellectual rights of the researchers. Comments:
public Dr. Mohsen Dadashi
Department of Clinical Psychology and Psychiatry, Beheshti Hospital, Ark Gate, Chahar Ra Saadi, Zanjan Province
Zanjan Iran (Islamic Republic of) 7531974143 +98 21 8670 5504 mohsen.dadashi@gmail.com Zanjan University of Medical Sciences scientific Dr. Mohsen Dadashi
Department of Clinical Psychology and Psychiatry, Beheshti Hospital, Ark Gate, Chahar Ra Saadi, Zanjan Province
Zanjan Iran (Islamic Republic of) 7531974143 +98 21 8675 6604 mohsen.dadashi@gmail.com Zanjan University of Medical Sciences Iran (Islamic Republic of) Having a diagnosis of schizophrenia Having the ability to write informed consent Experience positive symptoms despite a month of stabilization in medication dose The same dose and medicine Being a man Being right-handed Age 65_18 years The dose of antipsychotic medication used by the person is constant at the beginning and during the research Stabilization in drug treatment for at least 6 weeks 18 years 65 years Male Have a history of suicide and abuse of alcohol and substances other than caffeine and tobacco in the past month Have a history of neurological diseases such as Parkinson's, epilepsy, seizures, stroke and cardiovascular problems Having diseases related to the scalp Having a history of head trauma and the presence of a device or tool in the head Withdrawal from the study after absence in two consecutive sessions of treatment. F20 Schizophrenia Treatment - Other Treatment - Other Intervention group: Treatment with stimulation of extracranial direct current with a current of 2 mA for 20 minutes on the lateral dorsal forehead cortex will receive ten sessions for five days and two sessions a day. Control group: Treatment with stimulation of extracranial direct current with a current intensity of two milliamperes for 40 seconds on the lateral dorsal forehead cortex will receive ten sessions for five days and two sessions daily. Negative symptoms:Theoretical definition: It is one of the clinical symptoms in schizophrenia that includes superficial emotion, poor speech, lack of motivation, unhappiness and social transgression.Operational definition: The score that a person gets from the positive and negative symptoms of schizophrenia.Positive symptoms: Theoretical definition includes delusions, delusions, disturbed speech, and disturbed behavior that persist throughout a one-month period.Operational definition: The score that a person gets from the positive and negative symptoms of schizophrenia. Timepoint: Pre-test-post-test-one-month follow-up-quarterly follow-up. Method of measurement: The score that a person gets from the questionnaire for measuring positive and negative symptoms in schizophrenia. Working memory:Theoretical definition: means the ability to store and manipulate information in memory, which is an essential prerequisite for complex cognitive tasks such as learning, reasoning and comprehension. Timepoint: Pre-test-post-test-one-month follow-up-quarterly follow-up. Method of measurement: The score a person gets from the n back test. Zanjan University of Medical Sciences Approved 2021-05-25 Ethics Committee of Zanjan University of Medical Sciences Shahid Beheshti Hospital, Ark Gate, Saadi Crossroads, Zanjan Province zanjan Zanjan Iran (Islamic Republic of)