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IRCT20210611051539N1 IRCT 2021-06-19 Mazandaran University of Medical Sciences Effect of nano-Zataria multiflora supplement on cutaneous candidiasis Evaluation of antifungal supplement properties of Zataria multiflora-loaded nanostructural lipid carriers on cutaneous candidiasis 2021-07-06 anticipated 40 Complete https://irct.ir/trial/56815 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In order to observe random allocation, the site www.randomizer.org is used and using codes based on blocking people into 2 groups, even and odd codes are installed on the drug and placebo. Then, for each group of drugs and placebo, it is placed in a special envelope and the patient number and drug code are written on the envelope, Blinding description: The patients participating in the study, as well as the researcher, including the master student who is responsible for their dissertation, as well as the physicians who perform the intervention, are among the people who are blinded in the study. The drug and placebo are both placed in similar envelopes. The fellow doctors and graduate students who are performing the intervention are not aware of its contents. Only the drug code and the patient code will be stated in the questionnaire. But the executor is aware of the code as an analyst and assigns it to control and intervention groups. Participants, on the other hand, are not aware of the contents of the envelope, but will be informed that their supplement may be a placebo. 2-3 Cutaneous candidiasis. Intervention 1: Intervention group: For patients with cutaneous candidiasis (except onychomycosis), 1% thyme nano-gel which is made by Mazandaran University of Medical Sciences in 60 g tubes, is applied twice a day for a month. This intervention is used as an adjunct to the main antifungal drug prescribed by dermatologist. Intervention 2: Control group: For patients with cutaneous candidiasis (except onychomycosis), placebo is used as a gel which is made in Mazandaran University of Medical Sciences in 60 g tubes, is applied twice a day for a month. Placebo is used as an adjunct to the main antifungal drug prescribed by dermatologist. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.
public Dr. Maryam Moazeni
Shayan 3 Bldg, Ghaem 12 St., Ghaem St., Taleghani Blvd., Sari
Sari Iran (Islamic Republic of) 4817845423 +98 11 3325 7911 moazeni.maryam@gmail.com Mazandaran University of Medical Sciences scientific Dr. Maryam Moazeni
Shayan 3 Bldg, Ghaem 12 St., Ghaem St., Taleghani Blvd., Sari
Sari Iran (Islamic Republic of) 4817845423 +98 11 3325 7911 moazeni.maryam@gmail.com Mazandaran University of Medical Sciences Iran (Islamic Republic of) All patients presenting with mild-moderate cutaneous candidiasis and do not require treatment with systemic antifungals. 10 years no limit Both Taking antifungal drugs Children and infants in the age range of 0-10 years B37.2 Candidiasis of skin and nail Treatment - Drugs Treatment - Drugs Intervention group: For patients with cutaneous candidiasis (except onychomycosis), 1% thyme nano-gel which is made by Mazandaran University of Medical Sciences in 60 g tubes, is applied twice a day for a month. This intervention is used as an adjunct to the main antifungal drug prescribed by dermatologist. Control group: For patients with cutaneous candidiasis (except onychomycosis), placebo is used as a gel which is made in Mazandaran University of Medical Sciences in 60 g tubes, is applied twice a day for a month. Placebo is used as an adjunct to the main antifungal drug prescribed by dermatologist. Improvement of fungal lesions in terms of mycological criteria. Timepoint: Before the intervention, 2 and 4 weeks after the intervention. Method of measurement: Evaluation of clinical symptoms such as erythema, inflammation and pruritus and evaluation of negative direct examination and mycology culture. Mazandaran University of Medical Sciences Approved 2021-06-08 Ethics committee of Mazandaran University of Medical Sciences 5th Floor, Shayan 3 Bldg., Ghaem 12 St, Ghaem St., Taleghani Blvd., Sari Sari Mazandaran Iran (Islamic Republic of)