IRCT20210627051723N1 IRCT 2021-07-03 The University of Tehran The effect of combined exercise and L-arginine on adropine, VEGFR-2 and adhesive molecules in hypertensive postmenopausal women The effect of combined training and L-arginine ingestion on the serum levels of Adropin, VEGFR-2 and intercellular and vascular adhesion molecules in postmenopausal hypertensive women 2021-07-16 anticipated 40 Complete https://irct.ir/trial/57156 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Factorial, Purpose: Prevention, Randomization description: The subjects 'names are written on separate sheets of paper and placed in a container, then the subjects' names are randomly taken out and placed in the intervention or placebo group. The first 30 names are placed in the intervention group and the rest in the placebo gro, Blinding description: In order to eliminate the error caused by the awareness of the participants and the researcher Study on the type of treatment received and its possible impact on the research outcomeWe do it blindly in two directions.Because the placebo and L-arginine supplement are placed inside the capsule in exactly the same way, participants and researchers are not aware of the type of supplement they receive. 3 Hypertension. Intervention 1: Intervention group: L-arginine supplement group (L-arginine supplement daily and at a dose of 6 grams (three servings of 2 grams.). Intervention 2: Combined exercises will be performed for 8 weeks and three sessions per week. First, resistance training and a few minutes later, endurance training will be performe.). Intervention 3: Intervention group: Combined training group + L-arginine supplement (combined training will be performed for 8 weeks and three sessions per week. First, resistance training and a few minutes later, endurance training.At the same time, L-arginine supplement is taken daily and in the amount of 6 grams (three meals of 2 grams) every day.). Intervention 4: Control group:Placebo group (not participating in exercise and taking placebo. For 8 weeks, taking L-arginine-like capsules with white flour content (placebo) in the morning, evening and night, made by Darogostar company, in addition to daily activities of life.). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.