IRCT20161021030410N4 IRCT 2021-09-09 Babol University of Medical Sciences The effect of ischemic postconditioning on myocardial protection Evaluation of the effect of Ischemic postconditioning on myocardial protection in patients undergoing coronary artery bypass graft surgery 2021-09-05 anticipated 150 Complete https://irct.ir/trial/57471 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: The patients will be randomly divided into 3 groups of 50 subjects with six blocks and an allocation ratio of 1:1:1. The participants allocation sequence in three groups perform with a Randomizer software. Opaque sealed sequentially numbered envelops use for allocation concealment. 2 Cardiovascular Disease. Intervention 1: Control group: routine after heparin and cannulation of the aorta and right atrium and start the pump, aortic clamping and injection cardioplegin the aortic root and inducing arrest of the heart, anastomosis distal to the vascular coronary and after turning clamp of perfect for the partial, proximal anastomosis will be performed.In this group, immediately after removing the partial aortic clamp, the pump will be removed. Intervention 2: Intervention group: In perfusion group, 12 minutes after removal of the aortic partial clamp exits the pump without vascular grafts close by bulldog. Intervention 3: Intervention group: In Ipost group before leaving the pump, 3 minutes after removal of the aortic partial clamp, vascular grafts are closed by bulldogs for 3 minutes. again reopen these bulldogs for three minutes and close again for another 3 minutes (overall for 12 minutes after removing the aortic partial clamp) bulldogs are removed. then patient exits of pump. No - There is not a plan to make this available Justification or reason for not sharing IPD is .