]>
IRCT201411115362N21 IRCT 2015-01-19 Isfahan University of Medical Sciences Licorice gargling to decrease sore throat after surgery An evaluation of the efficacy of different doses of licorice gargling for attenuating postoperative sore throat after tracheal intubation 2013-01-01 anticipated 144 Complete https://irct.ir/trial/5750 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. 3 Condition 1: Postoperative Sore Throat (POST). Condition 2: Postextubation Cough. Intervention 1: Group A: Licorice (Gargling, 0.25 gram Licorice in 30 ml of water, 5min before operation, for 30 seconds). Intervention 2: Group B: Licorice (Gargling, 0.5 gram Licorice in 30 ml of water, 5min before operation, for 30 seconds). Intervention 3: Group C: Licorice (Gargling, 1 gram Licorice in 30 ml of water, 5min before operation, for 30 seconds). Intervention 4: Group D (Control group): Placebo (Gargling, only 30 ml of water, 5min before operation, for 30 seconds).
public Dr.Mohammadreza Safavi
Hezarjarib Street
Isfahan Iran (Islamic Republic of) +98 913 315 2416 safavi@med.mui.ac.ir Isfahan University of Medical Sciences scientific Dr.Mohammadreza Safavi
Hezarjarib Street
Isfahan Iran (Islamic Republic of) +98 913 315 2416 safavi@med.mui.ac.ir Isfahan University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria:Patients underwent any operation other than head and neck surgery under general anesthesia; aged between 18 and 65 years; with American Society of Anesthesia (ASA) physical status I and II; no NSAID use; no perioperative corticosteroid intake (from 24 hours before operation); no allergy or intolerance to licorice; no upper respiratory tract infection; without mallampati grade more than two. Exclusion criteria: Any change in anesthetic technique; requiring more than one attempt for intubation; not being extubated at the end of the surgery; re-intubation within the study period. 18 years 65 years Both R07.0 R05 Pain in throat Cough Prevention Treatment - Drugs Treatment - Drugs Treatment - Drugs Group A: Licorice (Gargling, 0.25 gram Licorice in 30 ml of water, 5min before operation, for 30 seconds) Group B: Licorice (Gargling, 0.5 gram Licorice in 30 ml of water, 5min before operation, for 30 seconds) Group C: Licorice (Gargling, 1 gram Licorice in 30 ml of water, 5min before operation, for 30 seconds) Group D (Control group): Placebo (Gargling, only 30 ml of water, 5min before operation, for 30 seconds) Postoperative Sore Throat. Timepoint: 0, 2, 4, and 24 hours after operation. Method of measurement: Visual Analogue Scale. Postextubation Cough. Timepoint: after extubation. Method of measurement: Observation. Patient Satisfation. Timepoint: 24 hours after operation. Method of measurement: Likert form asked from patient (very satisfied, satisfied, no opinion, dissatisfied, very dissatisfied). Isfahan University of Medical Sciences Approved 2012-06-13 Isfahan University of Medical Sciences Hezarjarib Street Isfahan Iran (Islamic Republic of)