]>
IRCT20210718051928N1 IRCT 2021-09-06 Esfahan University of Medical Sciences Comparison of three drug groups effectiveness, intravenous Lidocaine and Dexamethasone, intravenous Ketamine and Dexamethasone and Dexamethasone alone in the managment of respiratory complications after tonsillectomy. Comparison of three drug groups effectiveness, intravenous Lidocaine and Dexamethasone, intravenous Ketamine and Dexamethasone and Dexamethasone alone in the managment of respiratory complications after tonsillectomy. 2021-09-01 anticipated 100 Complete https://irct.ir/trial/57637 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Within the setting time we enter all patients who have the indication non-randomly. Patients are then divided into 4 groups according to the law of random allocation. The SPSS system randomly codes 100 patients, so that each patient who enters the operating room has a specific code based on how many people enter the operating room. For example, the fourth patient has code B and receives medication in this group, Blinding description: Patients in 4 groups receive the same volume of drugs and do not know the content of the drugs. The parents, the statistical researcher and the person collecting the data do not know the study group. The person preparing the medicine does not know the patients. 2-3 Respiratory complications after tonsillectomy. Intervention 1: Intervention group1: Dexamethasone 0.1 mg / kg and Lidocaine 1 mg / kg in a 5cc syring with the same volume witch is injected as a single dose before extubation. Intervention 2: Intervention group2: Ketamine 0.5 mg / kg and Dexamethasone 0.1 mg / kg prepared in a 5cc syring witch is injected as a single dose before extubation. Intervention 3: Intervention group3: Dexamethasone 0.1 mg / kg prepared in a 5cc syring with the same volume witch is injected as a single dose before extubation. Intervention 4: Control group4: recieve normal saline with the same volume(5 cc) intravenous befor extubation. Yes - There is a plan to make this available What will be shared: The questionnaire and statistical data will be published without individual patient data . When: After completing the research. To whom: Researchers from academic institutions will have access. Conditions: Any kind of scientific analysis is allowed. Where to obtain: Dr. Seyed Morteza Heidari and Somayeh Hoghughi, whose full contact information was provided in the previous sections. How to obtain: For a week after making the call, the information will be provided. Comments:
public Somayye Hoghughi
Isfahan univercity of medical science, Hezarjarib Ave
اصفهان Iran (Islamic Republic of) 81746-73461 +98 31 3240 3303 yameisam@yahoo.com Esfahan University of Medical Sciences scientific Somayye Hoghughi
Isfahan univercity of medical science
اصفهان Iran (Islamic Republic of) 81746-73461 +98 31 3240 3303 yameisam@yahoo.com Esfahan University of Medical Sciences Iran (Islamic Republic of) All ASA1 patients are candidates for elective tonsillectomy Age between 2-18 years Parental consent 2 years 18 years Both Active upper respiratory tract infection during the two weeks prior to surgery Active lower respiratory tract infection during the 5 weeks prior to surgery History of asthma History of allergy to Lidocaine , Dexamethasone and Ketamine ASA2 patients and higher J04.2 Acute laryngotracheitis Prevention Prevention Prevention Placebo Intervention group1: Dexamethasone 0.1 mg / kg and Lidocaine 1 mg / kg in a 5cc syring with the same volume witch is injected as a single dose before extubation. Intervention group2: Ketamine 0.5 mg / kg and Dexamethasone 0.1 mg / kg prepared in a 5cc syring witch is injected as a single dose before extubation. Intervention group3: Dexamethasone 0.1 mg / kg prepared in a 5cc syring with the same volume witch is injected as a single dose before extubation. Control group4: recieve normal saline with the same volume(5 cc) intravenous befor extubation. The percentage of people whose airway irritability score is 8-10. Timepoint: Every ten minutes after entering the recovery and the moment of leaving the recovery. Method of measurement: Use of airway irritability questionnaire. Isfahan univercity of medical science Approved 2021-08-30 Ethics committee of Isfahan University of Medical Sciences Isfahan University of Medical Sciences, Hezarjorib Ave Isfahan Isfehan Iran (Islamic Republic of)