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IRCT20101204005305N20 IRCT 2022-02-16 Kerman University of Medical Sciences Comparison of two methods using mineralized allogeneic bone graft with or without iPRF in the reconstruction of horizontal alveolar ridge defects. Histomorphometrical and radiological comparison of mineralized allogeneic bone graft with or without L-PRF in the reconstruction of horizontal alveolar ridge defects in a randomized controlled clinical trial. 2021-10-23 anticipated 20 Complete https://irct.ir/trial/57707 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization will be done with the minimization method. Randomization of 10 to 20 percent of the samples will be done in a simple way by tossing a coin, and then the participants will be divided into two intervention groups and control groups based on their gender in order to homogenize the groups, Blinding description: Two clinicians who are calibrated and blind to the study will perform all radiographic measurements. The demographic data of all radiographies will be removed and a code will be given to each radiography. A pathologist who is blind to the study will assess the prepared slides. For blindness, a code will be given to each slides. N/A Edentulous ridge width. Intervention 1: Control group: First a mid-crystal incision is made and then vertical release incisions with a gap tooth on each side to increase access. The flap is removed in full-thikness. Decoration is done. From Freeze Dried Bone Allogrft 0 granules2000-1000 microns. Kish texture replicator, Kish, Iran) is used. The bone marrow is moistened with sterile saline solution before use. After placement of the target area, it is completely covered by absorbable collagen membrane (thickness 0.4 to 0.6 microns. Kish tissue replicator, Kish, Iran). The membranes are fixed on the membranes by absorbable vicryl sutures (supa, Tehran, Iran) using the horizontal scrubber technique. Soft tissue closure is initially done with Supa, Iran (Supalon, 5-0) nylon sutures with 3 techniques: Horizontal mattress, interrupted and crisscross. 6 months after the agglomeration process, the implants are placed during the second surgery. Intervention 2: Intervention group: First, blood is taken from the patient's cephalic vein and centrifugation is performed on it to inject platelet rich fibrin. Then, in the operation stage, a mid-crystal incision is made and then the vertical releasing incisions are struck with a gap tooth on each side to increase. The flap is removed in full-thikness. Decoration is done. From Freeze Dried Bone Allogrft 0 granules2000-1000 microns. Kish texture replicator, Kish, Iran) is used with iPRF. The affected bone is moistened with sterile saline solution before use. After placing the desired area, it is completely covered by an absorbable collagen membrane (thickness 0.4 to 0.6 microns. Kish, Kish, Iran) tissue replicator. The membranes are fixed on the membranes by absorbable vicryl sutures (supa, Tehran, Iran) using the horizontal scrubber technique. The closure of the soft tissue is initially done with Supalon, Iran (Supalon 5-0) nylon sutures and with 3 horizontal mattress techniques, cut and crossed. 6 months after the agglomeration process, the implants are placed during the second operation. Yes - There is a plan to make this available What will be shared: Part of the data is shared after the people are made unrecognizable. When: 2023-2024 To whom: Academic persons Conditions: No special access criteria Where to obtain: E-mail:mmohammadi28@yhoo.com How to obtain: There are not details Comments:
public Mohammad Mohammadi
Shafa street, Dental School
kerman Iran (Islamic Republic of) 7618759689 +98 34 3211 9021 mmohammadi28@yahoo.com Kerman University of Medical Sciences scientific Mohammad Mohammadi
Shafa street
Kerman Iran (Islamic Republic of) 7618759689 +98 34 3211 9021 mmohammadi28@yahoo.com Kerman University of Medical Sciences Iran (Islamic Republic of) need to horizontal augmentation of alvolar bone for implant treatment (edentulous ridge width: 2/5 - 4 mm ) no limit no limit Both Use of more than 10 cigarettes per day Pregnancy Uncontrolled periodontal disease Use of bisphosphonate and corticosteroid Chemotherapy and radiotherapy Systematic diseases for example: non controlled diabetes; osteoporosis and immune deficiency Treatment - Surgery Treatment - Surgery Control group: First a mid-crystal incision is made and then vertical release incisions with a gap tooth on each side to increase access. The flap is removed in full-thikness. Decoration is done. From Freeze Dried Bone Allogrft 0 granules2000-1000 microns. Kish texture replicator, Kish, Iran) is used. The bone marrow is moistened with sterile saline solution before use. After placement of the target area, it is completely covered by absorbable collagen membrane (thickness 0.4 to 0.6 microns. Kish tissue replicator, Kish, Iran). The membranes are fixed on the membranes by absorbable vicryl sutures (supa, Tehran, Iran) using the horizontal scrubber technique. Soft tissue closure is initially done with Supa, Iran (Supalon, 5-0) nylon sutures with 3 techniques: Horizontal mattress, interrupted and crisscross. 6 months after the agglomeration process, the implants are placed during the second surgery. Intervention group: First, blood is taken from the patient's cephalic vein and centrifugation is performed on it to inject platelet rich fibrin. Then, in the operation stage, a mid-crystal incision is made and then the vertical releasing incisions are struck with a gap tooth on each side to increase. The flap is removed in full-thikness. Decoration is done. From Freeze Dried Bone Allogrft 0 granules2000-1000 microns. Kish texture replicator, Kish, Iran) is used with iPRF. The affected bone is moistened with sterile saline solution before use. After placing the desired area, it is completely covered by an absorbable collagen membrane (thickness 0.4 to 0.6 microns. Kish, Kish, Iran) tissue replicator. The membranes are fixed on the membranes by absorbable vicryl sutures (supa, Tehran, Iran) using the horizontal scrubber technique. The closure of the soft tissue is initially done with Supalon, Iran (Supalon 5-0) nylon sutures and with 3 horizontal mattress techniques, cut and crossed. 6 months after the agglomeration process, the implants are placed during the second operation. Horizontal edentulous ridge width. Timepoint: Measurement of edentulous ridge width by CT scan of the patient at the beginning of the study and 6 months after reconstructive surgery. Method of measurement: Bone width measurement from CBCT radiograph. Kerman University of Medical Sciences Approved 2021-09-06 Ethics committee of Kerman university of medical science Tahmasebabad crossroads, researches center Kerman Kerman Iran (Islamic Republic of)