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IRCT20081021001378N13 IRCT 2021-12-29 Mashhad University of Medical Sciences Effects of probiotics in bilirubin increase Comparison of the effectiveness of probiotics against bilirubin increase in neonates below 2500 gram. 2021-01-06 anticipated 100 Complete https://irct.ir/trial/57734 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The allocation of infants will be done using block methods. A random sequence will be generated using four blocks of sealedenvelope.com. The envelopes will be printed by the researcher after randomization and will be placed inside the envelopes and the envelope lids will be closed. Envelopes are numbered in random order. Then, we first explain the purpose of the study to the person and he / she will sign the informed consent and receive the intervention based on the envelope number and the order specified in it, Blinding description: Considering that the babies do not have the necessary knowledge in this regard and the mothers have not been informed about this study, the study is therefore one-way blind and only the researcher who is performing the study knows. 2-3 hyperbilirubinemia. Intervention 1: Intervention group: 5 drop pedilact zist takhmir probiotic .co. Iran daily for 3 days 5 ml/g from first day. And bilirubin level is measured every 24 hours for 7 days. Intervention 2: Control group: No pedilactzisttakhmir probiotic. Yes - There is a plan to make this available What will be shared: All data can be shared after patients are made unidentified When: data can be accessible 6 months after results are published To whom: Data can be accessible through an email to the corresponding author Conditions: data will be available for researchers in universities and other scientific institution Where to obtain: After sending a request email to the corresponding author , data will be sent in 1 month. How to obtain: Carrying out analysis on data is permitted Comments:
public Nazli Parizadeh
Ibn Sina Ave, Imam Reza Hospital, Mashhad, Iran
Mashhad Iran (Islamic Republic of) 9137913316 +98-051-385211121 parizadehnazli@gmail.com Mashhad University of Medical Sciences scientific Nazli Parizadeh
Ibn Sina Ave, Imam Reza Hospital, Mashhad, Iran
Mashhad Iran (Islamic Republic of) 9137913316 +98 51 3852 1121 parizadehnazli@gmail.com Mashhad University of Medical Sciences Iran (Islamic Republic of) Neonate weighting less than 2,500 grams are not in critical condition Do not have krenictrose Do not have ventilation Do not have heart failure Do not have asphyxia and no history of Rh incompatibility Do not have icterus 1 day 28 days Both Critical neonates Phototherapy P59.0 Neonatal jaundice associated with preterm delivery Treatment - Drugs Other Intervention group: 5 drop pedilact zist takhmir probiotic .co. Iran daily for 3 days 5 ml/g from first day. And bilirubin level is measured every 24 hours for 7 days. Control group: No pedilactzisttakhmir probiotic Bilirubin. Timepoint: Daily for 7 days. Method of measurement: Through the surface of the skin. Hospitalization period. Timepoint: Daily. Method of measurement: Number of days. Weight gain. Timepoint: Daily. Method of measurement: Balance. Mashhad University of Medical Sciences Approved 2019-06-12 Ethics committee of Mashhad University of Medical Sciences Ghoreshi Bul, Daneshgah St, Mashhad,Iran Mashhad Razavi Khorasan Iran (Islamic Republic of)