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IRCT20210802052051N1 IRCT 2021-08-29 Esfahan University of Medical Sciences Evaluation of the effect of bromelain on pain after root canal treatment Evaluation of the effects of bromelain and acetaminophen in reduce postoperative pain following root canal therapy with symptomatic irreversible pulpitis in comparision with placebo and acetaminophen 2021-09-04 anticipated 60 Complete https://irct.ir/trial/57965 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: In this study,a simple randomization method using a table of random number is used.in this study,wich includes 60 samples,the number 00 to 60 are asssigned to the samples.then we randomly select the table point in the row direction.we select numbers smaller than the size of the study population.the select number are the individual code of the community that is selected as the sample.we will continue this until the sample size is complete and reaches the number 60, Blinding description: This study is performed in a double-blind manner.Firstly a pharmacist makes anaheal and acetaminophen tablets with a similar apearance and codes one of them as Aa and the other as Ab. Then, an Aa tablet with an acetaminophen pill will be given to half of the patients and an Ab tablet with an acetaminophen will be given to the other half. 3 Pain after root canal therapy. Intervention 1: Control group:Half of the samples receiving acetaminophen 500 mg and placebo every 6 hours until the pain improved and their pain before treatment, 24, 12, 6 and 48 hours after treatment were marked on the VAS (Visual Analogue Scale) questionnaire. Intervention 2: Intervention group:Half of the samples who receive acetaminophen 500mg and Anaheal 500 mg of Promon Amin health brand every 6 hours until the pain improved and their pain before treatment, 24, 12, 6 and 48 hours after treatment were marked on the VAS (Visual Analogue Scale) questionnaire. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.
public Fatemeh Abbasi
Department of Oral Medicine, Dental research institute, Isfahan University of Medical Sciences, Isfahan, Iran
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3792 5514 f.abbasi@dnt.mui.ac.ir Esfahan University of Medical Sciences scientific Fatemeh Abbasi
Department of Oral Medicine, Dental research institute, Isfahan University of Medical Sciences, Isfahan, Iran
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3792 5514 f.abbasi@dnt.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) The age range of all patients be 10 years and older tooth Periapical tissue be normal 10 years no limit Both Pregnant women do not enter the study Patients who have kidney and coagulation problems Patients taking anticoagulants patient has a systemic problem K04.0 Pulpitis Placebo Treatment - Drugs Control group:Half of the samples receiving acetaminophen 500 mg and placebo every 6 hours until the pain improved and their pain before treatment, 24, 12, 6 and 48 hours after treatment were marked on the VAS (Visual Analogue Scale) questionnaire. Intervention group:Half of the samples who receive acetaminophen 500mg and Anaheal 500 mg of Promon Amin health brand every 6 hours until the pain improved and their pain before treatment, 24, 12, 6 and 48 hours after treatment were marked on the VAS (Visual Analogue Scale) questionnaire. Pain Score in Visual Analog Scale System (VAS). Timepoint: Before treatment and 6,12,24and 48hours after treatment. Method of measurement: Visual analog scale. Evaluation of the effecacy of bromelaine in reduce postoperative pain following root canal therapy secondary consequences can be a pain reduction score. Timepoint: To measure pain befor root canal therapy , 6 ,12 ,24 and 48 hours after root canal therapy is used . Method of measurement: Evaluation of the effecacy of bromelaine in reduce postoperative pain following root canal therapy secondary consequences pain reduction score Visual Analogue Scale can be used . Esfahan University of Medical Sciences Approved 2021-06-09 Ethics comittee of Isfahan University of Medical Sciences IsfahanUniversity Of Medical Science,Hezar jarib Ave Isfahan Isfehan Iran (Islamic Republic of)