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IRCT20210824052279N1 IRCT 2021-08-31 Islamic Azad University The Effects of 8 Weeks of Circuit Resistance Training on Some Inflammatory and Endothelial Markers in Pre-hypertensive Obese Women The Effects of 8 Weeks of Circuit Resistance Training on Some Inflammatory and Endothelial Markers in Pre-hypertensive Obese Women 2021-09-01 anticipated 24 Complete https://irct.ir/trial/58320 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: The researcher gives a special code or number to each member of the community. He then writes down the number of each of them on a small piece of paper or cardboard; then puts them into a box or container and mixes them. Then he takes out the cards one by one, writes down their number, and continues to do so until he chooses 24 numbers. When the number of samples is completed. The same method is used to determine the control and intervention groups. In this way, a number from 1 to 24 is assigned to participants, then writes on cards and puts in a bag. The first 12 numbers that are took out of the bag is assigned to the control group and the next 12 numbers to intervention group. N/A pre-hypertension. Intervention 1: Intervention group: CRT group will perform circuit resistance training for 8 weeks which according to the recommendations of the American Heart Association will be 40% 1RM for upper body and 60% 1RM for lower body movements.The training protocol is for 8 weeks, 3 sessions per week and each session is 50 to 60 minutes (15 minutes of warm-up, 30 minutes of weight training, 10 minutes of cooling). Resistance movements performs in the form of 3 circles and 9 stations, including four upper body movements (chest press, lat pull down, seated cable row, biceps cable curl) and three lower body movements (leg press, seated leg extension, leg curl), and two core-body movements (crunch and back extension) . The order of performing the movements is such that first the mid-torso movements and then the upper and lower torso movements are performed alternately. Intervention 2: Control group: All measurements will be performed like the intervention group 48 hours before and after the intervention, except that they will not have physical training during 8 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Hengameh Moradian
Sharyati street, Moradian apartment
Kermanshah Iran (Islamic Republic of) 6713986161 +98 83 3721 2165 hengameh.moradiyan@gmail.com Islamic Azad University scientific Hengameh Moradian
Sharyati
Kermanshah Iran (Islamic Republic of) 6713986161 +98 83 3721 2165 hengameh.moradiyan@gmail.com Islamic Azad University Iran (Islamic Republic of) They should be obese (BMI>,30). Their blood pressure must be about 120-139 and 80-89 mmHg. 40 years 50 years Female Subjects have any special disease or skeletal problems. They use weight loss medication or diet. I10 Essential (primary) hypertension Rehabilitation Rehabilitation Intervention group: CRT group will perform circuit resistance training for 8 weeks which according to the recommendations of the American Heart Association will be 40% 1RM for upper body and 60% 1RM for lower body movements.The training protocol is for 8 weeks, 3 sessions per week and each session is 50 to 60 minutes (15 minutes of warm-up, 30 minutes of weight training, 10 minutes of cooling). Resistance movements performs in the form of 3 circles and 9 stations, including four upper body movements (chest press, lat pull down, seated cable row, biceps cable curl) and three lower body movements (leg press, seated leg extension, leg curl), and two core-body movements (crunch and back extension) . The order of performing the movements is such that first the mid-torso movements and then the upper and lower torso movements are performed alternately. Control group: All measurements will be performed like the intervention group 48 hours before and after the intervention, except that they will not have physical training during 8 weeks. Blood pressure. Timepoint: 48 hours before and after intervention. Method of measurement: Barometer, Beurer, Germany. Anthropometric profiles. Timepoint: 48 hours before and after intervention. Method of measurement: Skinfold Caliper, Harpenden, UK- meter. Lipid profiles (Triglyceride, Cholesterol, Low density lipoprotein, High density lipoprotein). Timepoint: 48 hours before and after intervention. Method of measurement: Blood sampling, Pars azmoon kit, Tehran, Iran. Insulin resistance. Timepoint: 48 hours before and after intervention. Method of measurement: Blood sampling using fasting glucose and insulin, Mercodia kit, Iceland, Sweden. Inflammatory markers ( Interleukin-1 beta, Tumor necroes alpha). Timepoint: 48 hours before and after intervention. Method of measurement: Blood sampling, KPG company. Endothelial markers ( Endothelin-1 , Nitric oxide). Timepoint: 48 hours before and after intervention. Method of measurement: Blood sampling, Zellbio kit, Germany. Islamic Azad University Approved 2021-07-18 Ethics Committee of The Institute of Physical Education Sharyati street Kermanshah Kermanshah Iran (Islamic Republic of)