IRCT20090427001853N17 IRCT 2021-10-24 Urology Research Center, Guilan University of Medical Sciences Safety of omitting antibiotic prophylaxis prior to Transurethral Lithotripsy (TUL) Comparison of safety of omitting antibiotic prophylaxis prior to Transurethral Lithotripsy (TUL) in two groups of patients with and without positive urine culture referred to Razi Hospital in Rasht: a pilot study 2021-10-31 anticipated 50 Complete https://irct.ir/trial/58753 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Diagnostic. N/A Postoperative complication. Intervention 1: Intervention group: Omitting prophylactic antibiotic therapy prior to Transurethral Lithotripsy (TUL) in patients with positive urine culture in whom routinely antibiotics are continued until urine culture become negative. Intervention 2: Control group: Patients without positive urine culture in whom antibiotic is not prescribed as standard prior to Transurethral Lithotripsy (TUL). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to the possibility of prolonging the study and publication of the article, researchers will decide regarding the details of sharing the unidentifiable personal data of the participants after the end of the study and publication of the results in the form of an article.