]>
IRCT20130812014333N177 IRCT 2021-10-23 Kermanshah University of Medical Sciences Comparison of anesthesia with and without drug use on complications in patients undergoing gallbladder surgery A comparative study of free opioid anesthesia and standard general anesthesia on the complication amount cholecystectomy patient 2021-10-11 anticipated 62 Complete https://irct.ir/trial/58785 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The permutation random block is used for randomization. In this way, first, the total sample size and the ratio of sample size in groups are determined. Then, the number of samples will be selected from the table of random numbers of single-digit numbers between 0 and 9. For studies with two groups, the numbers 0-9 are divided into two equal blocks with a probability of assigning an individual to each block is 0.5. Block 4-0 for the first group and block 5-9 for the second treatment can be used. Based on the selected numbers from the table of random numbers and the determination of blocks, it is clear in which group each person who enters the study will be placed. 3 Cholecystectomy. Intervention 1: In the first intervention group, anesthesia is performed using narcotics (Sufentanil Abu Reihan Company dose of half a microgram per kilogram of body weight by injection). Intervention 2: In the second intervention group for anesthesia of patients from a combination of magnesium infusion (Samen company one to two mg) for auxiliary analgesia and low dose ketamine (Retekmedica company dose of 0.2 mg per kg body weight) for analgesia and dextmetomedin for sympatholysis Analgesia, anesthesia and lidocaine (Exir company dose of 1 mg per kilogram of body weight) are used for laryngoscopy and non-irritation and ketorolac (Abu Reihan company 60 mg) is used for pain during and after surgery. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information
public Mohammad Javad Alibakhshi
Emam Reza Hospital, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 mjalibakhshi@yahoo.com Kermanshah University of Medical Sciences scientific Dr. Alireza Ahmadi
Emam Reza Hospital, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 Alireza.Ahmadi@kums.ac.ir Kermanshah University of Medical Sciences Iran (Islamic Republic of) Patients who have not taken a long-acting analgesic in the last month Patients who are not addicted 18 years no limit Both Patients with serious chronic diseases including diabetes, tuberculosis, epilepsy; Cardiovascular and .. Patients who have received a vaccine or antidote within 1 month prior to screening Patients who have received an immunosuppressive drug one month before surgery Patients who are allergic to morphine or morphine compounds Pregnant people K91.86 Retained cholelithiasis following cholecystectomy Treatment - Drugs Treatment - Drugs In the first intervention group, anesthesia is performed using narcotics (Sufentanil Abu Reihan Company dose of half a microgram per kilogram of body weight by injection). In the second intervention group for anesthesia of patients from a combination of magnesium infusion (Samen company one to two mg) for auxiliary analgesia and low dose ketamine (Retekmedica company dose of 0.2 mg per kg body weight) for analgesia and dextmetomedin for sympatholysis Analgesia, anesthesia and lidocaine (Exir company dose of 1 mg per kilogram of body weight) are used for laryngoscopy and non-irritation and ketorolac (Abu Reihan company 60 mg) is used for pain during and after surgery. Pain after surgery. Timepoint: 5 hours after surgery, discharge time. Method of measurement: Based on Visual Pain Scale (VAS). Kermanshah University of Medical Sciences Approved 2021-08-31 Ethics committee of Kermanshah University of Medical Sciences Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences, Building No.2, Shahid Beheshti Boulevard Kermanshah Kermanshah Iran (Islamic Republic of)