<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20210817052212N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2021-11-12</date_registration>
      <primary_sponsor>Mohaghegh Ardabili University</primary_sponsor>
      <public_title>Effect of eight week continuance, interval and polarized training on serum level indexes of insulin-like growth factor-1 axis and performance in active young men</public_title>
      <acronym></acronym>
      <scientific_title>Comparison of the effectiveness of eight weeks of continuous, interval and bipolar training on serum indexes of growth hormone insulin-like growth factor-1axis and performance in active young men</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2022-11-20</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>40</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/58999</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Education/Guidance, Randomization description: After selecting the subjects, they were randomly divided into four homogeneous groups(Simple randomization), Blinding description: In this study, educators and data analysts will be kept blind.</study_design>
      <phase>N/A</phase>
      <hc_freetext>It is not a disease.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group 1: "Continuous exercise". The subjects of this group will include 10 minutes of warm-up with a variety of stretching, flexibility, walking and running. The main activity of the moderate to intense aerobic exercise group includes 30 to 50 minutes of continuous running with an intensity of 50-70% of the reserve heart rate (pressure perception of 12 to 15) and at the end 5 minutes of cooling down by walking and doing stretching exercises. Intervention 2: Second intervention group: "Periodic exercise". Exercises in this group include 10 minutes of warm-up with a variety of stretching, flexibility, walking and running, and the main activity of the group of subjects in this group includes 3 periods with 4 repetitions and 15-30 seconds of running with an intensity of 85-95% of the reserve heart rate. Pressure perception 16 to 19) in each repetition will be 30-30 seconds of active rest after each repetition and 3 minutes of active rest after each period (active rest in the range of 40-50% of the stored heart rate). Intervention 3: Third intervention group: "Bipolar exercise". The bipolar workout group will perform 80-70% of the main workout volume (30 minutes) with light to moderate intensity (50-60% reserve heart rate) and the remaining 20-30% with 85-95% reserve heart rate intensity, In this way, two periods with 3 repetitions of 15-30 seconds, which will have an active rest of 30-60 seconds after each repetition and an active rest of 3 minutes after each period. Intervention 4: Control group: "No training program".During this eight-week period, they will avoid regular physical activity.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>No - There is not a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for not sharing IPD is The need is not seen</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Behzad Azadi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Mohaghegh Ardabil University., End of University Street., Ardabil</address>
        <city>Ardabil</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>5619913131</zip>
        <telephone>+98 45 3150 5005</telephone>
        <email>behzadazadi2009@gmail.com</email>
        <affiliation>Mohaghegh Ardabili University</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Lotfali Bolboli</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Mohaghegh Ardabil University., End of University Street., Ardabil</address>
        <city>Adrdabil</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>5619913131</zip>
        <telephone>+98 45 3150 5355</telephone>
        <email>sbolboli@yahoo.com</email>
        <affiliation>Mohaghegh Ardabili University</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Non metabolic disease
Age: 25-18 years
Fat percentage between 22-17%
Body mass index between 19-25 kg / m2</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>25 years</agemax>
      <gender>Male</gender>
      <exclusion_criteria>smoking
Age outside the scope of the study
Having an underlying disease
Have a training program in the last six months</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>N/A</i_code>
      <i_code>N/A</i_code>
      <i_code>N/A</i_code>
      <i_code>N/A</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group 1: "Continuous exercise". The subjects of this group will include 10 minutes of warm-up with a variety of stretching, flexibility, walking and running. The main activity of the moderate to intense aerobic exercise group includes 30 to 50 minutes of continuous running with an intensity of 50-70% of the reserve heart rate (pressure perception of 12 to 15) and at the end 5 minutes of cooling down by walking and doing stretching exercises.</i_keyword>
      <i_keyword>Second intervention group: "Periodic exercise". Exercises in this group include 10 minutes of warm-up with a variety of stretching, flexibility, walking and running, and the main activity of the group of subjects in this group includes 3 periods with 4 repetitions and 15-30 seconds of running with an intensity of 85-95% of the reserve heart rate. Pressure perception 16 to 19) in each repetition will be 30-30 seconds of active rest after each repetition and 3 minutes of active rest after each period (active rest in the range of 40-50% of the stored heart rate)</i_keyword>
      <i_keyword>Third intervention group: "Bipolar exercise". The bipolar workout group will perform 80-70% of the main workout volume (30 minutes) with light to moderate intensity (50-60% reserve heart rate) and the remaining 20-30% with 85-95% reserve heart rate intensity, In this way, two periods with 3 repetitions of 15-30 seconds, which will have an active rest of 30-60 seconds after each repetition and an active rest of 3 minutes after each period.</i_keyword>
      <i_keyword>Control group: "No training program".During this eight-week period, they will avoid regular physical activity.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Serum indices of Growth Hormone - Insulin-like growth factor-1 axis. Timepoint: Before the intervention, after the first session and after 8 weeks. Method of measurement: Blood sampling.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Performance of active young men. Timepoint: Before and after the intervention. Method of measurement: Bruce and Wingate test.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Mohaghegh Ardabili University</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2020-09-25</approval_date>
        <contact_name>Ethics committee of Tabriz University</contact_name>
        <contact_address>University of Tabriz., University Square.,Tabriz Tabriz East Azarbaijan Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
