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IRCT20210909052418N1 IRCT 2021-10-31 Tabriz University of Medical Sciences The comparison of the effect of tetracycline sterile ophthalmic ointment as an adjvant in peri-implantitis treatment The comparison of the effect of tetracycline sterile ophthalmic ointment as an adjvant to mechanical debridement and mechanical debridement alone in peri-implantitis treatment 2021-11-06 anticipated 32 Complete https://irct.ir/trial/59244 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization will be using sealed envelopes, of which 32 envelopes will be selected in total and will be divided into two categories of 16, which include groups A and B. At the beginning of the patients' arrival, the secretary of the clinic randomly provides the envelopes to the patients and the patients select them and enter the examination area with the envelopes, and then the dentist will determine the group of patients using the envelopes, Blinding description: The person evaluates the outcome of patients compared to blind study groups. Patients will be treated by the first and second study supervisors. 2-3 peri-implantitis. Intervention 1: Intervention group: After local anesthesia (Xylocaine Dental (lidocaine HCl)) and isolation and drying of tetracycline ointment (AEROTEX) surfaces by placing a flexible needle (cannula blunt) in the periodontal pouch without trauma or damage to periodontal tissue. (Periodontal cover is not placed.) And then patients will undergo mechanical debridement. Intervention 2: Control group: After local anesthesia (Xylocaine Dental (lidocaine HCl)) and isolation and drying, patients will undergo mechanical debridement. Yes - There is a plan to make this available What will be shared: Study data is categorized and coded with no identifiable individuals. When: Access to study data after publication of the result is available in the journal. To whom: Anyone interested in using the data can access the study data. Conditions: Study data can be used for comparison with other results. Where to obtain: Refer to the study's scientific or public accountability person for data. How to obtain: The request will be sent by email to person responsible for scientific or public inquiries. Comments:
public Mohammad amin Mesforoush
No 43, badamchilar Alley, gharabaghi ha St, Mansour Av
Tabriz Iran (Islamic Republic of) 5155892837 +98 41 3237 3382 drm.aminmesforoush@yahoo.com Tabriz University of Medical Sciences scientific Mohammad amin Mesforoush
No 43, badamchilar Alley, gharabaghi ha St, Mansour Av
Tabriz Iran (Islamic Republic of) 5155892837 +98 41 3237 3382 drm.aminmesforoush@yahoo.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Presence of pre-implant disease No history of pre-implant surgery treatment PD>6 mm Positive BOP BOL<2mm No use of antibiotics and mouthwash and periodontal treatment in the last 6 weeks. No use of antibiotics and mouthwash and periodontal treatment in the last 6 weeks 20 years no limit Both Pregnancy and breast feeding Using anticoagulants Allergy to tetracycline sterile eye ointment Underlying disease (diabetes, kidney disorders, etc.) Smoking M27.69 Other endosseous dental implant failure Treatment - Drugs Treatment - Drugs Intervention group: After local anesthesia (Xylocaine Dental (lidocaine HCl)) and isolation and drying of tetracycline ointment (AEROTEX) surfaces by placing a flexible needle (cannula blunt) in the periodontal pouch without trauma or damage to periodontal tissue. (Periodontal cover is not placed.) And then patients will undergo mechanical debridement. Control group: After local anesthesia (Xylocaine Dental (lidocaine HCl)) and isolation and drying, patients will undergo mechanical debridement. Presence or absence of plaque on tooth and implant surfaces (mesial, distal, buccal and lingual surfaces). Timepoint: 1 and 3 months after the intervention. Method of measurement: Clinical dental examination. The distance between the gingival margin and the depth of the envelope is in millimeters. Timepoint: 1 and 3 months after the intervention. Method of measurement: Clinical dental examination. Presence or absence of bleeding after probing. Timepoint: 1 and 3 months after the intervention. Method of measurement: Clinical dental examination. The distance between the acrylic stent and the depth of the pocket. Timepoint: 1 and 3 months after the intervention. Method of measurement: Clinical dental examination. Tabriz University of Medical Sciences Approved 2021-08-30 Ethics committee of Vice chancellor for research, Tabriz University of Medicalُ Sciences Vice chancellor for research, Tabriz University of Medical Sceinces, Daneshgah Square Tabriz East Azarbaijan Iran (Islamic Republic of)