]>
IRCT20211012052740N1 IRCT 2021-10-16 Oroumia University of Medical Sciences Effect of Variable Doses of Metronidazole in Treatment of Helicobacterpylori Comparison of Therapeutic Effects of Metronidazole in Variable Doses in Eradication of Helicobacterpylori in Dyspeptic Patients 2021-12-06 anticipated 170 Complete https://irct.ir/trial/59268 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization is Done in Simple Method And Patients are Divided into Control and Intervention Groups in a List of Codes Prepared by Random Allocation Software.The Subjects are Assigned into Different Groups by Random Allocation. Allocation Concealment is Obtained by Maintaining the Randomization List by Study Statistician, Blinding description: Patients Participating in the Study are not be Informed about the Type of their Treatment Regimen. 3 Helicobacter pylori Infection. Intervention 1: Intervention group: Group B Receives Following Medications for 14 Days: Tab Metronidazole 500 mg TDS, Omeprazole 20 mg BID, Amoxicillin 1000 mg BID, Bismuth Subcitrate 135 mg BID. Intervention 2: Control group: Group A Receives Following Medications for 14 Days: Tab Metronidazole 500 mg BID, Omeprazole 20 mg BID, Amoxicillin 1000 mg BID, Bismuth Subcitrate 135 mg BID. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more Information
public Mohammadreza Mohammad Hoseiny Azar
Amar Ave., Tadbir's Clinic
Urmia Iran (Islamic Republic of) 5714783734 +98 44 3346 2420 mohammadazar@gmail.com Oroumia University of Medical Sciences scientific Mohammadreza Mohammad Hoseiny Azar
Amar Ave., Tadbir's Clinic
Urmia Iran (Islamic Republic of) 5714783734 +98 44 3346 2420 mohammadazar@gmail.com Oroumia University of Medical Sciences Iran (Islamic Republic of) Dyspeptic Patients with Positive Helicobacterpylori Stool Antigen Test Older than 18 Years Old Persons 18 years no limit Both No Referring After Taking the Medication Taking Medications for Less than 10 Days Pregnant or Breastfeeding Women Patients with the History of Major Cardiac, Pulmonary, Renal or Hepatic Disease History of Known Side Effects to the Medications of Therapeutic Regimen Taking Antibiotic during the Last Month B96.81 Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere Treatment - Drugs Treatment - Drugs Intervention group: Group B Receives Following Medications for 14 Days: Tab Metronidazole 500 mg TDS, Omeprazole 20 mg BID, Amoxicillin 1000 mg BID, Bismuth Subcitrate 135 mg BID Control group: Group A Receives Following Medications for 14 Days: Tab Metronidazole 500 mg BID, Omeprazole 20 mg BID, Amoxicillin 1000 mg BID, Bismuth Subcitrate 135 mg BID Eradication of Helicobacter pylori Infection. Timepoint: Four Weeks after the Termination of Treatment. Method of measurement: Helicobacter pylori Stool Antigen Test. Drug Adverse Effects Including: Nausa, Abdominal Pain, Metallic Taste, Diarrhea. Timepoint: Four Weeks after Starting the Treatment. Method of measurement: Questionnaire. The Tolerance to Accepting the Treatment (Taking Medications more than 10 Days). Timepoint: Two Weeks after Starting the Treatment. Method of measurement: Questionnaire. Oroumia University of Medical Sciences Approved 2021-08-15 Ethics committee of Urmia University of Medical Sciences Urjans Alley, resalat Ave., Urmia University of Medical Sciences Urmia West Azarbaijan Iran (Islamic Republic of)