IRCT20190608043840N1 IRCT 2023-01-22 Shahid Beheshti University of Medical Sciences Evaluation of the efficacy of Maa-al-shaeer (product based on barley seeds) on radiotherapy induced dysuria Evaluation of efficacy of Maa-al-shaeer (An Iranian medicine product based on barley seeds) in preventing and reducing the severity of radiotherapy-induced dysuria in prostate cancer patients; a double-blind randomized clinical trial 2023-02-01 anticipated 70 Complete https://irct.ir/trial/59594 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Simple Randomization. Randomization is done using R software version 4.1.2, and we will use the randomization list generated using R software. In order to conduct this study, first, using the available method, patients who meet the conditions for entering the study, after completing the consent form, will enter the study until the number of calculated samples is complete. In the next step, in order to homogenize and control the background and confounding variables in the intervention and control groups, the block randomization method will be used to assign patients to two groups. For this purpose and according to the calculated sample size, 5 blocks of 14 blocks will be generated using R software. In each block, the interventions are randomly assigned to people with a ratio of 1:1. Since the shape of the drug and the placebo are completely similar and the labels on the cans of the interventions (drug or placebo) are prepared by a statistician (using R software) and sticked in the pharmaceutical laboratory, so, the participants and the researcher are all blind to it, Blinding description: Double Blind. In this study, the barley product is prepared in the form of powder and is packed in a can and coded after putting a label. Placebo is also prepared with the same particle size and color as the drug in the same packaging as the drug and is coded. Therefore, until the encoding, it is not possible for the participants, principle investigator, healthcare providers, data collectors, outcome assessors, manuscript writers to distinguish the drug from the placebo. 3 Prostate Cancer, Radiotherapy-induced dysuria, Urogenital radiotherapy complications. Intervention 1: Intervention group: Twice a day, every 12 hours, one measure of "Maa-al-shaeer" (malted barley powder which was prepared by the school of Traditional Medicine of Shahid Beheshti University of Medical Sciences) is dissolved in a glass of lukewarm water and consumed after meals. Each measure of powder is equivalent to 7.5 cc of powder and the intervention period is four weeks from the start of radiation therapy and the follow-up period is four weeks (without intervention). Intervention 2: Control group: Twice a day, every 12 hours, one measure of placebo powder (which was prepared by the school of Traditional Medicine of Shahid Beheshti University of Medical Sciences) is dissolved in a glass of lukewarm water and consumed after meals. Each measure of powder is equivalent to 7.5 cc of powder and the intervention period is four weeks from the start of radiation therapy and the follow-up period is four weeks (without intervention). No - There is not a plan to make this available Justification or reason for not sharing IPD is The study has not yet started, after the study is completed a decision will be made about sharing the participants' non-identifiable personal data.