IRCT20211023052849N2 IRCT 2022-03-09 Tehran University of Medical Sciences The effect of curcumin on septic patients The effect of curcumin supplementation on inflammatory factors and prognosis in septic ICU patients 2021-12-06 anticipated 60 Complete https://irct.ir/trial/59762 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization lists are computer-based by a statistician and the participants and project managers will be completely unaware (blind) about the intervention and control groups. Placebo capsules are identical capsules containing the same amount of maltodextrin. Both curcumin and placebo (Maltodexterin) capsules are produced by Arjuna Natural Extract, India. The concealments of supplements will be done by a third person, and the participants and investigators are not aware of the groups’ assignments until the end of analysis, Blinding description: Capsules are inside a sealed pocket with a specific code. Both the investigator and the nurse are unaware of the realation between the code and the type of capsule (curcumin or placebo). 2-3 sepsis. Intervention 1: Intervention group: curcumin. Intervention 2: Control group: placebo. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information