IRCT20200506047325N1 IRCT 2021-11-18 Golestan University of Medical Sciences Evaluation of anti-hypertensive effect of jujube fruit Investigation of antihypertensive effect of antioxidant enriched Ziziphus jujuba fruit extract in patients with primary hypertension: A randomized, double-blind, placebo controlled clinical trial 2023-04-21 anticipated 48 Complete https://irct.ir/trial/59980 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The random assignment list will be computer generated with a 1:1 allocation, stratified by recruitment site, using random block size of four. Using concealed in sequentially numbered, sealed, opaque envelopes (SNOSE), participants will enter the blocks in such a way that an equal number of each assigned group. Allocation will be done by randomly selecting one of the arrangements and assigning the next part of the participants to the study groups according to the specified sequence. And kept by the hospital pharmacist of the center, Blinding description: To maintain blindness in patients, the drug and placebo are the same in shape and appearance; Also, the evaluator is not aware of the type of drugs in the intervention groups, so that multi-digit numerical codes are written on the drug packages that only the main person in charge of the research is aware of. N/A Hypertension. Intervention 1: Intervention group: Receiving routine drug treatment + enriched antioxidant extract of Ziziphus jujuba fruit for 12 weeks (3 months). Patients will be evaluated for symptoms at 14 weeks and 16 weeks after the end of the study. Intervention 2: Control group: Receiving routine drugs+ placebo for 12 weeks (3 months). No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information.