IRCT20210611051539N2 IRCT 2021-12-25 Mazandaran University of Medical Sciences effect of nano-zataria multiflora supplement on dermatophytosis evaluation of antifungal supplement properties of zataria multiflura - loaded nanostructural lipid carriers on dermatophytosis 2021-12-22 anticipated 80 Complete https://irct.ir/trial/59989 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In order to observe random allocation, patients will divided into group A and B and simple randomization is performed individually using Random number table . Allocation concealmen is done using non transparent sealed envelopes. Specializing of even and odd codes perform on the envelop for drug and placebo and only the main researcher aware of them, Blinding description: The patients participating in the study, as well as the researcher, including the master student who is responsible for their dissertation, as well as the physicians who perform the intervention, are among the people who are blinded in the study. The drug and placebo are both placed in similar envelopes. The fellow doctors and graduate students who are performing the intervention are not aware of its contents. Only the drug code and the patient code will be stated in the questionnaire. But the executor is aware of the code as an analyst and assigns it to control and intervention groups. Participants, on the other hand, are not aware of the contents of the envelope, but will be informed that their supplement may be a placebo. 2-3 Dermatophytosis. Intervention 1: Intervention group: for patients with dermatophytosis(exept tinea angum and tinea capitis)1%thyme nano-gel which is made by mazandaran university of medical sciences in 60 g tubes , is applied twice a day for a month . this intervention is used as an adjunct to the main antifungal drug prescribed by dermatologist. Intervention 2: Control group: for patient with dermatophytosis(except tinea angum and tinea capitis), placebo is used as a gel which is made in mazandaran university of medical science in 60g tube , is applied twice a day for a month. placebo is used as an adjunct to the main antifungal drug prescribed by dermatologist. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is there is no more information