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IRCT20170108031818N1 IRCT 2021-11-29 Gorgan University of Medical Sciences The effect of albuterol spray on hypoxia and bronchospasm in patients with chronic obstructive pulmonary disease (COPD) The effect of albuterol spray-on hypoxia and bronchospasm in patients with chronic obstructive pulmonary disease (COPD) under general anesthesia 2021-11-06 anticipated 120 Complete https://irct.ir/trial/60010 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: -, Randomization description: Participants in the study were assigned to the intervention (B) and control (A) groups by block randomization. In this way, using a dice that has 6 faces, the samples are assigned to their groups. A number is written on each side and each number is assigned to one of the blocks of the table, which has its own special mode. it shows. Group A (albuterol) and group B (no albuterol), Blinding description: Blinding in this study is double-blinding. So that both the patient did not know in which treatment group and the investigator (Investigator) were not aware of the patient's treatment group. The method of blinding was such that the esteemed supervisor filled the contents of the spray and the sprays were given to the anesthesia resident student who was the main presenter of the current dissertation. The evaluator, who was a resident student, did not know the contents of the sprays. 3 Chronic pulmonary obstruction(COPD). Intervention group: The patient receives 2 puffs of albuterol spray (2.5 micrograms per puff) 20 minutes before anesthesia. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.
public mahrokh maddah
5 Azar St., Gorgan
gorgan Iran (Islamic Republic of) 4915789465 +98 17 3217 7419 mehravar10261@goums.ac.ir Gorgan University of Medical Sciences scientific mahrokh maddah
5 Azar St., Gorgan
gorgan Iran (Islamic Republic of) 4915789465 +98 17 3217 7419 mehravar10261@goums.ac.ir Gorgan University of Medical Sciences Iran (Islamic Republic of) The patient is a smoker ASA is class 1 and 2 The patient has a history of COPD 35 years no limit Both The patient develops bronchospasm during the operation The surgery lasted more than 3 hours Pulmonary artery pressure is greater than 25 mm Hg Changes in blood pressure, heart rate and drop in severity by 20% of baseline J44. 9 J44. 9 Treatment - Drugs Intervention group: The patient receives 2 puffs of albuterol spray (2.5 micrograms per puff) 20 minutes before anesthesia Wheezing. Timepoint: once. After intubation of the endotracheal tube. Method of measurement: Using a medical earphone, the patient's lungs can be heard. Frequent coughing. Timepoint: 2 times - before anesthesia and after ecstasy. Method of measurement: By observing the appearance of the patient. Bronchospasm. Timepoint: 1 time. After anesthesia. Method of measurement: If the patient is intubated, bronchospasm is suspected by the anesthesia ventilator storage bag if the storage bag tightens and is considered positive and recorded. Gorgan University of Medical Sciences Approved 2021-10-03 Ethics committee of Golestan University of Medical Sciences shastkola blv. gorgan gorgan Golestan Iran (Islamic Republic of)