]>
IRCT20170510033909N13 IRCT 2022-01-29 Islamic Azad University, Isfahan Branch (Khorasgan), Research Deputy The effect of supplementation and exercise on indicators of heart damage and oxidative stress in individuals Addicted The effect of 8 weeks of Royal Jelly supplementation and cache training on cardiac injury indices and oxidative stress in opium addicts quitting methadone 2021-12-22 anticipated 80 Complete https://irct.ir/trial/60459 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Randomization method: Simple randomization; Randomization Tool: Random Number Table; Randomization Unit: Individual; In order to use a table of random numbers, the researcher will first determine the reading position of the table numbers. The numbers will then be considered for different groups. For example, zero to twenty-four for intervention A, twenty-five to forty-nine for intervention B, fifty to seventy-four for group C, and seventy-five to nine for group D. Then we will touch one of the numbers and move in one of the predetermined directions. The numbers will be recorded and assigned to four groups: Exercise with cache, use Royal Jelly, combination and control. In order to hide random allocation, the method of coded boxes with random sequence will be used. This method uses a number of boxes that are numbered randomly. Adequate sealing of the boxes, their apparent similarity and their weight will be ensured. N/A Addicted. Intervention 1: Intervention group 1 : For eight weeks, Royal Jelly was consumed daily as an oral gel at a dose of 100 mg per kilogram of body weight. Intervention 2: Intervention group 2 : Exercise with Cache : Subjects performed resistance exercises using Traband for 8 weeks and 3 consecutive sessions per week for 60 minutes each session. Each workout included 10 minutes of warm-up, 40 minutes of core training, and 10 minutes of cooling. Intervention 3: Intervention group 3 : Exercise with royal jelly supplements Subjects performed resistance exercises using Traband for 8 weeks and 3 consecutive sessions per week for 60 minutes each session. Royal jelly was also consumed daily as a oral gel at a dose of 100 mg per kilogram of body weight. Intervention 4: Control group: No intervention, only follow up. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is After the study
public Farzaneh Taghian
Khorasgan University, Arghavanie St, Isfahan
Isfahan Iran (Islamic Republic of) 8183895183 +98 31335002352 F_taghian@yahoo.com Islamic Azad University scientific Farzaneh Taghian
Khorasgan University, Arghavanie St, Isfahan
Isfahan Iran (Islamic Republic of) 8183895153 +98 81 8389 5183 F_taghian@yahoo.com Islamic Azad University Iran (Islamic Republic of) Gender Type of addiction: Opium Age range 25 to 45 years 25 years 45 years Male No heart disease Not participating in sports in the last year F19.20 Other psychoactive substance dependence, uncomplicated N/A Rehabilitation Rehabilitation N/A Intervention group 1 : For eight weeks, Royal Jelly was consumed daily as an oral gel at a dose of 100 mg per kilogram of body weight. Intervention group 2 : Exercise with Cache : Subjects performed resistance exercises using Traband for 8 weeks and 3 consecutive sessions per week for 60 minutes each session. Each workout included 10 minutes of warm-up, 40 minutes of core training, and 10 minutes of cooling Intervention group 3 : Exercise with royal jelly supplements Subjects performed resistance exercises using Traband for 8 weeks and 3 consecutive sessions per week for 60 minutes each session. Royal jelly was also consumed daily as a oral gel at a dose of 100 mg per kilogram of body weight. Control group: No intervention, only follow up Malondialdehyde. Timepoint: At the beginning and end of 8 weeks of study. Method of measurement: Serum concentration of CGRP by ELISA method using the Cayman Chemical Monobind USA. Superoxide dismutase. Timepoint: At the beginning and end of 8 weeks of study. Method of measurement: Serum concentration of superoxide dismutase is measured by ELISA method using Ransell kit made by Randox company. Islamic Azad University, Isfahan Branch (Khorasgan), Research Deputy Approved 2019-02-24 Ethics Committee on Research Islamic Azad University - Isfahan Branch (Khorasgan) University Blvd, Arghavanie, East Gay Street, Isfahan Isfahan Isfehan Iran (Islamic Republic of)