IRCT20211210053344N1 IRCT 2021-12-28 Iran University of Medical Sciences Comparison of the effect of electrosurgery with cryosurgery in the treatment of sebaceous hyperplasia, seborrheic keratosis, cherry angioma and skin tag Evaluation of efficacy and safety of electrosurgery in comparison with cryosurgery in patients with sebaceous hyperplasia, seborrheic keratosis, cherry angioma and skin tag: A controlled randomized clinical trial 2022-01-21 anticipated 128 Complete https://irct.ir/trial/60633 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The lesions of the patients are divided into two groups using a simple randomization method, so that out of 32 sealed bags, one bag will be randomly selected for each lesion. Each envelope contains the letter a or b: a for the electrosurgery group and b for the cryosurgery group. 2-3 Condition 1: sebaceous hyperplasia. Condition 2: seborrheic keratosis. Condition 3: cherry angioma. Condition 4: skin tag. Intervention 1: Intervention group 1: For patients in this group, electrosurgery is done at the first session and repeated 4 weeks later if necessary (maximum 2 sessions). Electrosurgery is performed with biterminal monopolar electrocoagulation mode and with 20 to 40 degrees, after anesthesia with 0.2 to 0.5 cc of 2% lidocaine. Intervention 2: Intervention group 2: For patients in this group, cryosurgery is done at the first session and repeated 2 and 4 weeks later if necessary (maximum 3 sessions). Cryosurgery is performed using a spray and directly with liquid nitrogen, from a distance of 1 to 2 cm to freeze the entire lesion with a margin of 1 mm. In order to prevent complications, two cycles of cryosurgery are performed for each lesion. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.