IRCT201503175623N40 IRCT 2015-03-28 Kashan University of Medical Sciences Effect of supplementation in treatment of Coronary Heart Disease Effects of folate supplementation on on carotid intima media thickness (CIMT) and metabolic profiles among type 2 diabetes patients with coronary heart disease 2015-03-06 anticipated 60 Complete https://irct.ir/trial/6070 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: At study baseline and after stratification for pre-intervention BMI and age, subjects will be randomly divided into two groups to take folate supplements (n = 30) or placebo (n = 30). Randomization will be done by the use of computer-generated random numbers, Blinding description: Participants, investigators or the assessors of the outcomes are unaware of the study groups.Randomization and allocation will be concealed from the researchers and participants until the final analyses are completed. Another person at the clinic, who is not involved in the trial and not aware of random sequences, will be assigned the participants to the numbered bottles of capsules. 3 Coronary Heart Disease. Intervention 1: Intervention group: Folate tablet, 5 mg, daily, for 12 weeks orally. Intervention 2: Control group: Placebo tablet, daily, for 12 weeks orally. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available