IRCT20211216053428N1 IRCT 2022-02-22 Vice chancellery of Research and Technology, Isfahan University of Medical Sciences Herbal cream of borage, evening primrose, calendula, and leek versus topical mometasone 0.01% for atopic dermatitis Efficacy of topical herbal cream formulation consisting of borage, evening primrose, calendula and, leeks versus topical mometasone 0.01% in the treatment of atopic dermatitis 2022-01-20 anticipated 62 Complete https://irct.ir/trial/61162 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Individual simple randomization using a table of random numbers generated by the Random Allocation software by a statistician unaware of the study. To perform allocation concealment, the same statistician will write the name of the groups on a piece of paper and put them in numbered envelopes based on the randomization table. The envelopes will then be sealed. Patient recruitment will be done by the investigator blinded to the content of the envelopes. An envelope will be allocated to each patient upon entering the study and the investigator will be unaware of which group the next patient will be allocated to, Blinding description: The physician responsible for lesion assessment will be blinded to the grouping of patients. Both drugs will be available in unidentifiable forms to the patients. 3 Atopic dermatitis. Intervention 1: Intervention group: topical herbal cream consisting of borage, evening primrose, calendula, and leeks daily for a month and tapered during the next month. Intervention 2: Control group: topical mometasone 0.01% daily for a month and tapered during the next month. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information