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IRCT20220108053665N1 IRCT 2022-01-24 Tabriz University of Medical Sciences The effect of using sodium hypochlorite detergent at different temperatures and concentrations on pain intensity after endodontic treatment comparison of pain scale after single-visit root canal treatment by different temperatures and concentrations of NaOCl in mandibular molars with irreversible pulpitis: Double-blind randomized clinical trial 2022-01-17 anticipated 72 Complete https://irct.ir/trial/61169 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: All stages of treatment will be performed in Tabriz Dental School. These 72 people are randomly assigned to the 6 groups mentioned using RandList software. All random numbers are written on a piece of paper. The sheets are folded and placed in a container. For each number, one of the groups is selected. The syringes containing the washing solution are covered with a layer of opaque coating. Each patient chooses a sheet and uses one of the detergents for that patient based on the selected number. Thus, neither the patient nor the researcher is aware of the type of treatment chosen and the study will be double blind, Blinding description: The syringes containing the washing solution are covered with a layer of opaque coating. Each patient chooses a sheet and uses one of the detergents for that patient based on the selected number. Thus, neither the patient nor the researcher is aware of the type of treatment chosen and the study will be double blind. To blind the study, all steps of sodium hypochlorite solution preparation will be performed by a trained assistant who has no role in the clinical process, and to prevent the researcher from feeling the temperature of the washing solutions, an insulating coating will be used on the washing syringes. N/A Irreversible pulpitis. Intervention 1: Intervention group 1: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 1% sodium hypochlorite as a detergent at 40 ° C. Intervention 2: Intervention group 2: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 0.5% sodium hypochlorite as a detergent at 22° C. Intervention 3: Intervention group 3: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 0.5% sodium hypochlorite as a detergent at 40 ° C. Intervention 4: Intervention group 4: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 1% sodium hypochlorite as a detergent at 2.5° C. Intervention 5: Intervention group 5: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 0.5% sodium hypochlorite as a detergent at 2.5° C. Intervention 6: Intervention group 6: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 1% sodium hypochlorite as a detergent at 22° C. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Hadi Mokhtari Zanuzi
Dentistry faculty, Tabriz University of Medical Sciences, Golgasht
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5921 mokhtari.z.h@gmail.com Tabriz University of Medical Sciences scientific Hadi Mokhtari Zanuzi
Dentistry faculty, Tabriz University of Medical Sciences, Golgasht
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 5921 mokhtari.z.h@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Systemically healthy patient Patient age 18-65 years No hypersensitivity to epinephrine and sodium hypochlorite No facial paraesthesia Do not take any palliatives 12 hours before treatment Do not take any drugs that Anesthesia interferes No history of trauma No pathological envelope during probing Completion of ethical questionnaire and willingness to participate in the study Lower molar teeth with irreversible pulpitis 18 years 65 years Both No lip anesthesia after 15 minutes of block injection8 Pain for no reason before treatment Pregnancy and lactation Severe periodontal disease Teeth that can not be isolated with a rubberdam Root canal calcification Tooth with severe unrestorable caries Use of a specific drug or narcotic K04.02 Irreversible pulpitis N/A N/A N/A N/A N/A N/A Intervention group 1: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 1% sodium hypochlorite as a detergent at 40 ° C Intervention group 2: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 0.5% sodium hypochlorite as a detergent at 22° C Intervention group 3: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 0.5% sodium hypochlorite as a detergent at 40 ° C Intervention group 4: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 1% sodium hypochlorite as a detergent at 2.5° C Intervention group 5: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 0.5% sodium hypochlorite as a detergent at 2.5° C Intervention group 6: Patients who have mandibular molars with irreversible pulpitis and are treated with root canal using 1% sodium hypochlorite as a detergent at 22° C Intensity of pain. Timepoint: Immediately after treatment, 3, 24, 48, 72 hours and 7 days after treatment. Method of measurement: visual analogue scale. Tabriz University of Medical Sciences Approved 2021-12-27 Ethics Committee of Tabriz University of Medical Sciences Central office of Tabriz University of Medical Sciences, Golgasht Ave, Azadi Blvd Tabriz East Azarbaijan Iran (Islamic Republic of)