IRCT201704205623N108 IRCT 2017-04-27 Iran University of Medical Sciences Effect of supplementation therapy in treatment of women with gestational diabetes Clinical trial of the effect of synbiotic supplementation compared with the placebo on pregnancy outcomes in women with gestational diabetes 2016-04-19 anticipated 60 Complete https://irct.ir/trial/6138 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: To decrease potential confounding effects, all participants according to balanced blocked randomisation will be randomly allocated into two treatment groups to take either supplement or placebo. Randomization will be done by the use of Stat Trek software, Blinding description: Randomization and allocation will be concealed from the researchers and participants until the final analyses are completed. Another person at the Clinic who is not involved in the trial and not aware of random sequences will allocate the numbered bottles of capsules to participants. Supplements and placebo are in the same packaging at the pharmaceutical company. Only the code is written on the packages. Patients and researcher do not know the type of drug and after analyzing the data, packet codes are decoded. 3 Gestational diabetes. Intervention 1: Control group: Placebo oral capsule (Tak Gen Zist, Tehran, Iran), daily, for 6 weeks. Intervention 2: Intervention group: Synbiotic oral capsule containing three strains of Lactobacillus acidophilus (2×109 CFU/g), Lactobacillus casei (2×109 CFU/g) and Bifidobacterium bifidum (2×109 CFU/g) (Tak Gen Zist, Tehran, Iran), 0.8 g inulin, daily, for 6 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available.