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IRCT20220119053769N1 IRCT 2022-01-28 Kashan University of Medical Sciences The effect of probiotic supplement on reducing oxidative stress and sperm quality in patients with asthenospermia The effect of probiotic supplement on reducing oxidative stress and sperm quality in patients with asthenospermia 2021-09-11 anticipated 20 Complete https://irct.ir/trial/61455 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, participants are randomly divided into two groups of control and intervention by random allocation software in individual units. Then, the number of each patient is given to the software and the patient group, ie intervention or control, is determined, Blinding description: This study has two aspects of blindness in which participants and evaluators of blind outcome. And randomization is done by random allocation software. Participants are randomly divided into intervention or control groups by random allocation software. Then, if they are in the intervention group, they will receive medicine, and if they are in the control group, they will receive a placebo, which is quite similar to medicine. But patients do not know whether they are receiving medication or not. Outcome assessors are also unaware of the group of participants and record their findings based on patient numbers. 2-3 Asthenospermia. Intervention 1: Intervention group: FAMILACT probiotic with a dose of 109 CFU. Intervention 2: Control group: Plasbo. Yes - There is a plan to make this available What will be shared: Primary and secondary outcome data will be published. When: After studying and analyzing the data To whom: All researchers Conditions: There is nothing wrong with using data provided the source is mentioned. Where to obtain: To the IRCT site How to obtain: Six months after the study Comments:
public Dr. Ghazaleh Meshkdanian
Kashan - 15 Khordad Square, Shahrdari Street
Kashan Iran (Islamic Republic of) 8715973474 +98 31 5544 3022 g_moshkdanian@yahoo.com Kashan University of Medical Sciences scientific Dr. Ghazaleh Meshkdanian
Kashan - 15 Khordad Square, Shahrdari Street
Kashan Iran (Islamic Republic of) 8715973474 +98 31 5544 3022 g_moshkdanian@yahoo.com Kashan University of Medical Sciences Iran (Islamic Republic of) People with asthenospermia and infertility problems due to abnormal sperm motility 18 years 40 years Male People outside the age group of 18-40 People who take certain medications to treat infertility People on a diet rich in probiotics People with asthenospermia who are forced to take certain medications during the illness N46 Male infertility Treatment - Drugs Treatment - Drugs Intervention group: FAMILACT probiotic with a dose of 109 CFU Control group: Plasbo Sperm and semen parameters. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram. Measurement of malondialdehyde (MDA) semen. Timepoint: Before intervention and after intervention. Method of measurement: Eliza. DNA fragmentation index test. Timepoint: Before intervention and after intervention. Method of measurement: Using Acidic Aniline Blue staining. Kashan University of Medical Sciences Approved 2021-08-14 Ethics Committee of Kashan University of Medical Sciences Kashan - 15 Khordad Square, Shahrdari St., Kashan University of Medical Sciences Kashan Isfehan Iran (Islamic Republic of)