IRCT20220223054107N1 IRCT 2022-02-25 Shahid Beheshti University of Medical Sciences The effect of oral care using Artificial saliva to control dry mouth in patients with COVID-19 under non-invasive mechanical ventilation: A quasi-experimental study The effect of oral care using Artificial saliva to control dry mouth in patients with COVID-19 under non-invasive mechanical ventilation: A quasi-experimental study 2022-03-01 anticipated 80 Complete https://irct.ir/trial/62123 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 3 COVID-19 patients. Intervention 1: Control group: This group receives only routine care (Chlorhexidine mouthwash 0.2% and normal saline) . Intervention 2: Intervention group: In this group, in addition to routine care (Chlorhexidine mouthwash 0.2% and normal saline), mucosamin synthetic saliva spray is also used 3 times a day for 3 days. Initially, on the first day of patients with COVID-19 use of non-invasive mechanical ventilation, demographic information and the results of the initial oral assessment of patients will be recorded, then the patient's oral condition will be examined daily for three days. Examination and evaluation of patients's mouth, in 4 stages including (day zero: before the start of non-invasive mechanical ventilation, first day: one day after the use of non-invasive mechanical ventilation until the third day (3 days after the use of non-invasive mechanical ventilation) Will be done by the Oral Dryness Scale (BOAS). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.