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IRCT20101130005280N48 IRCT 2022-03-03 Mashhad University of Medical Sciences The efficacy of adding Boswellia serrata The efficacy of adding Boswellia serrata on cognitive impairment in patients with schizophrenia 2022-03-26 anticipated 40 Complete https://irct.ir/trial/62200 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: This is how random numbers are prepared with the help of Randomaize.com. According to the number of research samples, a number of envelopes with wrappers Alumni (in order to avoid the clarity of the contents of the envelopes), are prepared and each of the random sequences created on a card is recorded and the cards inside the envelopes are better named. In order to maintain a random sequence, also on the outer surface of the envelopes. The issuance number is done in the same way. Finally, the lids of the letter envelopes are glued and placed inside a box, respectively. At the beginning of the registration of participants, based on the order of entry of eligible participants into the study, one of the envelopes of the letter is opened in order and the envelopes have the odd number of the control group and the envelopes have an even number, Blinding description: People under study and outcome assessor are fully aware of the subject of research and the purpose and process of the study, and after filling out the consent and according to the entry conditions, will enter the study of the contents of the envelope and to which group they are assigned (control and intervention) (Because they do not predict the outcome) will be unaware. 3 Schizophrenia. Intervention 1: Intervention group: In parallel, by administering 750 mg capsules of frankincense resin 3 times a day and placebo containing 750 mg of starch powder 3 times a day along with other available treatments for schizophrenia. Weeks 6 and 12 are assessed by PANSS, stroop, digit span, wisconsin, and Wechsler tests. Intervention 2: Control group: They undergo existing treatments for schizophrenia and are assessed at 6 and 12 weeks by PANSS, stroop test, digit span, wisconsin, and Wechsler memory tests. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is After finishing work, consult with colleagues and it will be published if all members
public Mohammadreza Fayazibordbar
Ibn-e-Sina Hospita, Bu-Ali Sq., Amel Blvd., Mashhad.
Mashhad Iran (Islamic Republic of) 919583134 +98 51 3711 2701 fayyazimr@mums.ac.ir Mashhad University of Medical Sciences scientific Mohammadreza Fayazibordbar
Ibn-e-Sina Hospita, Bu-Ali Sq., Amel Blvd., Mashhad.
Mashhad Iran (Islamic Republic of) 919583134 +98 51 3711 2701 fayyazimr@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) All patients with a confirmed diagnosis of schizophrenia according to DSM5 Age range 18 to 36 years Completion of the consent form by their legal guardian. Patients should have a trusted caregiver who monitors the patient's medication use. Education level: At least 8 classes. 18 years 36 years Both Existence of serious accompanying cognitive disorders. Having other psychiatric disorders. Existence of other medical diseases that affect cognition, such as head trauma and epilepsy Consumption of substances other than cigarettes Pregnant or lactating patient Do not have the ability and focus to perform tests F20 Schizophrenia Placebo Treatment - Drugs Intervention group: In parallel, by administering 750 mg capsules of frankincense resin 3 times a day and placebo containing 750 mg of starch powder 3 times a day along with other available treatments for schizophrenia. Weeks 6 and 12 are assessed by PANSS, stroop, digit span, wisconsin, and Wechsler tests Control group: They undergo existing treatments for schizophrenia and are assessed at 6 and 12 weeks by PANSS, stroop test, digit span, wisconsin, and Wechsler memory tests. Patient quality of life. Timepoint: Before the intervention and after 3 months of drug use. Method of measurement: PANSS tests, stroop test, digit span, wisconsin, Wechsler memory. Mashhad University of Medical Sciences Approved 2019-08-27 Ethics committee of Mashhad University of Medical Sciences Central Building of Mashhad University of Medical Sciences (Ghorshi), Daneshgah 16, Daneshgah Street Mashhad Razavi Khorasan Iran (Islamic Republic of)