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IRCT20220307054213N1 IRCT 2022-05-26 Esfahan University of Medical Sciences Comparative study of the effect of dexmedetomidine and remifentanil on the quality of endotracheal intubation with videolaryngoscope in patients with neck trauma Comparative study of the effect of dexmedetomidine and remifentanil on the quality of endotracheal intubation with videolaryngoscope in patients with neck trauma 2022-04-19 anticipated 80 Complete https://irct.ir/trial/62390 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Based on random blocks (blocks of 4) are divided into 2 groups of intervention and control. Randomization tool is random allocation. People are randomly divided into two groups, ie it is not known in advance which patient in which group Is utilizing random tool maker, Blinding description: Patients and health care providers and individuals in the role of data collection are blind to the study, ie the patient does not know which group he is in. The physician in charge of intubation also does not know what part the patient is anesthetized with.the collector of data is also blind to the study. 3 Intratracheal intubation with videolaryngoscope in patients with neck trauma. Intervention 1: Intervention group: group anesthetized by dexmedetomidine2 cc of dexmedetomodetomidine equivalent to 200 μμ in a 50 cc syringe is mixed with 0.9% normal saline c48 and injected at a rate of 1 g / kgμ1 for 10 minutes as loading and then at a dose of 0.5 g / kg / hμ. Main brand Not intended. Intervention 2: Intervention group: group anesthetized by remifentanil.mg 2 mg remifentanil with 0.48% cc normal saline is administered at a loading dose of 0.75 μ / kgμ for 10 minutes and then 0.1 g / kg / minμ as maintenance.No brand is intended. Yes - There is a plan to make this available What will be shared: Information about key variables can be shared after being unidentified When: after finishing the project To whom: All researchers in academic institutions Conditions: For further review of the published article Where to obtain: Send request to email masoudifar@med.mui.ac.ir How to obtain: Will be sent as soon as the person requests Comments:
public Dr.Mehrdad Masoudifar
Hezarjarib
Isfahan Iran (Islamic Republic of) 81746-73461 +98 31 3620 1992 masoudifar@med.mui.ac.ir Esfahan University of Medical Sciences scientific Dr.Mehrdad Masoudifar
Hezarjarib
Isfahan Iran (Islamic Republic of) 81746-73461 +98 31336201992 masoudifar@med.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) Age 18-60 years old from both genders candidate for neck neck trauma surgery ASA class 1 or 2 Informed consent malmpathy class 1 to 3 BMI less than 30 non sedative or opioid user non betablocker user 18 years 60 years Both Inability to intubating the patient XIX Injury, poisoning and certain other consequences of external causes Treatment - Drugs Treatment - Drugs Intervention group: group anesthetized by dexmedetomidine2 cc of dexmedetomodetomidine equivalent to 200 μμ in a 50 cc syringe is mixed with 0.9% normal saline c48 and injected at a rate of 1 g / kgμ1 for 10 minutes as loading and then at a dose of 0.5 g / kg / hμ. Main brand Not intended. Intervention group: group anesthetized by remifentanil.mg 2 mg remifentanil with 0.48% cc normal saline is administered at a loading dose of 0.75 μ / kgμ for 10 minutes and then 0.1 g / kg / minμ as maintenance.No brand is intended. Time needed to intubation. Timepoint: At the beginning of intervention. Method of measurement: Stopwatch. Number of successful intubation. Timepoint: at the beginning of intervention. Method of measurement: Counting. Systolic blood pressure. Timepoint: 0,1,3,5,10,15 minutes after intervention. Method of measurement: manometer. Esfahan University of Medical Sciences Approved 2022-03-06 Ethics committee of Isafahan university of medical sciences Hezarjarib Isfahan Isfehan Iran (Islamic Republic of)