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IRCT201102065774N1 IRCT 2011-07-24 vice-chancellor for research of Shahid Beheshti University of Medical Sciences The role of procalcitonin in sepsis Efficacy of procalcitonin level measurement in diagnosis of early antimicrobial resistance in patient with sepsis in emergency department 2011-07-23 anticipated 150 Complete https://irct.ir/trial/6267 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Diagnostic. 2-3 Condition 1: Sepsis. Condition 2: procalcitonin. Immunoluminoassy of serum procalcitonin in patient with sepsis, Blood sampling, Lumbar puncture.
public Ali Arhami Dolatabadi
Shahid Madani St, Immam hosein hospital
Tehran Iran (Islamic Republic of) 1617763141 00982177558081- 00982188251234 ali_arhami@sbmu.ac.ir; aliarhami@yahoo.com Shahid Beheshti University of Medical Sciences scientific Ali Arhami Dolatabadi
Shahid Madani St, Immam Hosein hospital
Tehran Iran (Islamic Republic of) 1617763141 00982177558081-00982188251234 ali_arhami@sbmu.ac.ir; aliarhami@yahoo.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: All patients with clinical findings suggesting sepsis, All patients with clinical findings of systemic inflammatory response syndrome Exclusion criteria: All patients with clinical findings of systemic inflammatory response syndrome from non bacterial origin, viral or parasitic infections, patients who receive corticosteroids on immunosuppressive drugs, history of immunodeficiency, patient with central venous catheter and premature infant no limit no limit Both B90-B94 R70-R79 Sequelae of infectious and parasitic diseases Abnormal findings on examination of blood, without diagnosis Diagnosis Immunoluminoassy of serum procalcitonin in patient with sepsis, Blood sampling, Lumbar puncture Procalcitonin. Timepoint: before and 6 hr and 24 hr after empiric antibiotic administration. Method of measurement: Immunoluminoassay ng/mL. Antibiogram. Timepoint: One time. Method of measurement: Resistantant, sensitive. Empiric antibiotic. Timepoint: one time, after blood sampling withdrawn. Method of measurement: based on united state infectious disease guideline. Time of clinical sign improved. Timepoint: Daily. Method of measurement: Clinical sign(fever). Prognosis(death). Timepoint: Death. Method of measurement: Clinically. Prognosis(life). Timepoint: Life. Method of measurement: Clinically. Thyroid tumor. Timepoint: One time. Method of measurement: Clinical and laboratory investigation. Immunosuppression. Timepoint: One time. Method of measurement: Clinical and laboratory investigation. vice-chancellor for research of Shahid Beheshti University of Medical Sciences Approved 2011-02-27 Ethics committee of Shahid Beheshti University of Medical Scinces Tabnank St, Yaman St, Shahid Chamran highway Tehran Iran (Islamic Republic of)