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IRCT201111255786N2 IRCT 2012-03-04 Vicechancellor for research, Urmia University of Medical Sciences The effect of terazosin and tolterodine on ureterl stent related symptoms US= Ureteral stent IPSS= International Prostate Symptom Score LUTS= lower urinary tract symptom V The effect of terazosin and tolterodine on ureterl stent related symptoms 2011-12-31 anticipated 100 Complete https://irct.ir/trial/6281 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2-3 Ureteral stent (Double-J stent) related symptoms. Intervention 1: Group1: Placebo same as tolterodine and terazosin dose. Intervention 2: Group2: Terazosin 2mg BID. Intervention 3: Group3: Tolterodine 2mg Daily. Intervention 4: Group4: Tolterodine 2mg Daily + Terazosin 2mg BID.
public Yousef Rezaei
Urmia University of Medicam Sciences, Urmia, Iran
Urmia Iran (Islamic Republic of) +98 44 1223 4897 yousefrezaei1986@gmail.com Faculty of medicine, Urmia University of Medical Sciences scientific Ali Tehranchi
Imam khomeini hospital, Ershad Blvd, Urmia,Iran
Urmia Iran (Islamic Republic of) +98 44 1345 9542 drtehranchi@yahoo.com Urology and Nephrology Research Center, Department of Urology Iran (Islamic Republic of) Exclusion criteria:‎ ‎1)‎‏ ‏Prior history of pelvic surgery‏ ‏ ‎2) Prior history of Transurethral Resection of the either Prostate or Bladder Tumor ‎3) Benign prostate hyperplasia‎ ‎4) Recent or recurrent urinary tract infection ‎5) Chronic medication with -blockers or Anti-cholinergic ‎6) Pregnancy‎ ‎7) Prostatitis ‎8) Prostate cancer‎ ‎9) Bilateral ureteroscopy or ureteral stenting‎ ‎10) Age >18 and <55 ‎11) Stone size >20 mm‎ ‎12) Diabetes‎ ‏13‏‎) Bladder Outlet Obstruction Inclusion criteria: If a patient dose not meet any exclusion criteria and to be undergone double-J stent indwelling. 18 years 55 years Both N20, N20.1 Calculus of kidney, Calculus of ureter, Calculus of kidney with calculus of ureter, Hydronephrosis with ureteropelvic junction obstruction Placebo Treatment - Drugs Treatment - Drugs Treatment - Drugs Group1: Placebo same as tolterodine and terazosin dose Group2: Terazosin 2mg BID Group3: Tolterodine 2mg Daily Group4: Tolterodine 2mg Daily + Terazosin 2mg BID Lower Urinary Tract Symptoms. Timepoint: before intervention, 14days after intervention, stent removal time. Method of measurement: IPSS(International Prostate Symptom Score) and VAS(Visual Analogue Scale). Drug complications. Timepoint: Stent removal time. Method of measurement: Getting history from patient. Amount of analgesic consumption. Timepoint: Stent removal time. Method of measurement: Getting history from patient. UUNRC 01 clinicaltrial.gov Vicechancellor for research, Urmia University of Medical Sciences Approved 2011-12-03 Local ethic's committee of Urmia University of Medical Sciences Urmia University of Medical Sciences, Resalat Blvd, Urmia,Iran Urmia Iran (Islamic Republic of)