IRCT20210216050373N4 IRCT 2022-05-28 Tehran University of Medical Sciences The evaluation the effect of nanocurcommin in people living with HIV Evaluation of safety and efficiency of curcumin in the immune system and viral load of patient with HIV 2022-07-06 anticipated 100 Complete https://irct.ir/trial/62847 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Randomization description: In this study, a simple randomization method will be used. Random number table is a set of numbers that are generated completely randomly and are tabulated. Firstly, we determine the direction of the random number table and then we decide to read the random number table from above. Then we consider even numbers for the intervention group and odd numbers for the control group. 1 The effect of nanocurrcomin in HIV treatment. Intervention 1: Control group: A group that only takes routine HIV medications. Intervention 2: Intervention group: A group that uses nanocurcumin in addition to basic drugs to treat HIV. This drug contains curcumin, which is active except turmeric root. The other two main curcuminoids (dimethoxy curcumin and bis dimethoxy curcumin) are also components of this drug. This medicine is a 40 mg tablet daily for 3 months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to classified information of the patients