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IRCT20100119003106N44 IRCT 2023-02-16 Islamic Azad University Evaluation the response rate in major depressive disorder after taking Sertraline as a predictive factor base on motor cortex magnetic brain stimulation. Evaluation the response rate in major depressive disorder after taking sertraline as a predictive factor base on motor cortex magnetic brain stimulation. 2022-05-22 anticipated 48 Complete https://irct.ir/trial/62889 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment. 2-3 The effect of sertraline in major depressive disorder. Intervention 1: Intervention group :48 patients with major depression in the age group of 18 to 65 years will be selected by a psychiatrist or by using the Hamilton and beck questionnaire and the amount of motor evoked potential will be measured for them before taking the drug. Intervention 2: Control group: including 48 patients with major depression in the age group of 18 to 65 years, confirmed by a psychiatrist and will be selected using the Hamilton and Beck questionnaire, and the amount of motor evoked potential will be measured for them after taking 100 mg of serteralin. Yes - There is a plan to make this available What will be shared: Evaluation the response rate in major depressive disorder after taking sertraline as a predictive factor base on motor cortex magnetic brain stimulation. When: Just after the articles publication. To whom: For all investigators. Conditions: No more information. Where to obtain: Applicants can refer to the department of clinical pharmacy faculty of pharmacy, Tehran medical science Islamic area university Dr. Hashemian or contact the researcher by sending email to mahsimamoosavandi1@gmail.com or calling 09127834959. How to obtain: the information. Applicant must commit themselves to mention the source. If the request is sent six months after the publication of research information the researcher will send the data to the requesting party by email within a week. Comments:
public mahsima moosavandi
No. 99, Yasman Alley, Yakhchal Street., Shariati Avenue. 99
tehran Iran (Islamic Republic of) 19356466 +98 21 2264 0599 mahsimamoosavani1@gmail.com Islamic Azad University scientific Dr. farshad Hashemian
No. 99, Yasman Alley, Yakhchal Street., Shariati Avenue
tehran Iran (Islamic Republic of) 19356466 +98 21 2264 0599 Hashemian.f@Iaups.ac.ir Islamic Azad University Iran (Islamic Republic of) evaluation major depressive disorder Psychiatrist or Hamilton 24 question Age between 18-65 question provided by the Having informed satisfaction and motivation to cooperate and participate in completing the researcher No history of psychiatrist medication use in last two week 18 years 65 years Both If a person has a specific acute neurological/ psychological disorder at the same time F32 Major depressive disorder, single episode Treatment - Drugs Treatment - Drugs Intervention group :48 patients with major depression in the age group of 18 to 65 years will be selected by a psychiatrist or by using the Hamilton and beck questionnaire and the amount of motor evoked potential will be measured for them before taking the drug. Control group: including 48 patients with major depression in the age group of 18 to 65 years, confirmed by a psychiatrist and will be selected using the Hamilton and Beck questionnaire, and the amount of motor evoked potential will be measured for them after taking 100 mg of serteralin. Determining the Motor evoked potential of patients through transcranial magnetic stimulation. Timepoint: Before taking sertraline and 2 hours after taking sertraline. Method of measurement: Comparison of Motor evoked potential of patients before and after taking serteralin. Hamilton and Beck depression questionnaire. Timepoint: Before taking sertraline and after taking sertraline. Method of measurement: Comparison of Hamilton and beck depression score of patients before and after taking serteralin. Research Unit of Azad Islamic University of Medical Sciences Approved 2022-02-28 Ethics committee of Islamic Azad university of Tehran medical sciences No. 99, Yakhchal Street, Gholhak Dr. Shariati St. TEHRAN Tehran Iran (Islamic Republic of)