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IRCT20220412054507N1 IRCT 2022-04-18 Islamic Azad University effect of doxycycline on asthma_like infection Evaluation of the effect of doxycycline on asthma_like infection 2021-04-12 anticipated 50 Complete https://irct.ir/trial/62891 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Using https://www.randomizer.org, we randomly assign 50 codes to two groups of doxycycline and placebo. The drugs are all in the form of capsules with the same shape, size, color and packaging but different codes. Medications are given to a co-worker who is in our clinic and is unaware of the type of medication or placebo and the disease, Blinding description: Medications are given to a co-worker who is in our clinic and is unaware of the type of medication or placebo and the disease, so that patients can be given a package of medication. 2-3 Asthma. Intervention 1: Intervention group: This group is taken 100 mg doxycycline Cap twice a day for 15 days. Intervention 2: Control group: This group is taken 100 mg placebo twice a day for 15 days. Yes - There is a plan to make this available What will be shared: All data is potentially shareable after unidentifiable individuals When: Unlimited To whom: Students and researchers Conditions: To conduct further research and expand knowledge Where to obtain: Sending email is needed How to obtain: Sending email is needed Comments:
public Sara Nejati Zahmatkesh
No 29, Rodaki 20, Rodaki st, Piroozi 4st,Piroozi Blv
Mashhad Iran (Islamic Republic of) 9177894815 0098513878965 Sarah.nejati.z@gmail.com Islamic Azad University scientific Dr Majid Mirsadraee
Iman bulding, kosar 4 and 6, Kosar blvd
Mashhad Iran (Islamic Republic of) 973870 4347 +98 51 3870 4347 Majidmirsadraee@yahoo.com Islamic Azad University Iran (Islamic Republic of) Patient older than 18 years with new infection with asthma-like symptoms and signs for more than 6 weeks like cough,dyspnea,stimulation with environmental factors and obstructive spirometry with reversibility of more than 12% with short-acting beta-agonist 18 years no limit Both Pregnancy/GERD/Sensivity to Doxycycline/ Liver diseases J45 Asthma Treatment - Drugs Placebo Intervention group: This group is taken 100 mg doxycycline Cap twice a day for 15 days. Control group: This group is taken 100 mg placebo twice a day for 15 days Asthma treatment. Timepoint: In the beginning of the study, one and two months after taking the drugs. Method of measurement: ACT Questionnaire, Spirometry and Clinical sings and symptoms. Sponcer Approved 2021-05-19 Ethics Committee in Research, Islamic Azad University, Mashhad Ostad Yusofi Street, Emamieh Boulevard ,GhasemAbad, Mashhad, Iran Mashhad Razavi Khorasan Iran (Islamic Republic of)