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IRCT20220529055014N1 IRCT 2022-06-15 Bam University of Medical Sciences Effect of N-acetylcysteine ​​and bromhexine pneumothorax Comparison of the efficacy of N-acetylcysteine and bromhexine in patients with pneumothorax 2022-06-22 anticipated 50 Complete https://irct.ir/trial/63838 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Crossover, Purpose: Treatment, Randomization description: First determine a total sample size then randomly Assign a set of them to group A and the rest to group B. For example, in a study with a sample size of 50 people, 25 balls for intervention group A and 25 balls for group Intervention B is placed inside a lottery container and then the balls are randomly recorded without being replaced from the container and the resulting sequence is recorded. 3 Pneumothorax. Intervention 1: Intervention group: In this group, pneumothorax patients are treated orally for one week by implanting chest tube and taking bromhexine tablets, a product of Aveh Sina Pharmaceutical Company, at a dose of 8 mg once a day. Then the patient is photographed chest and in case of recovery of pneumothorax, the time required for chest tube exit is recorded and examined. Intervention 2: Intervention group: In this group, pneumothorax patients are treated by chest tube implantation and N-acetylcysteine, a product of Aveh Sina Pharmaceutical Company, at a dose of 600 mg as a solution in 30cc of water, every 12 hours orally for one week. Take. Then the patient is photographed chest and in case of recovery of pneumothorax, the time required for chest tube exit is recorded and examined. Yes - There is a plan to make this available What will be shared: Clinical information (including therapeutic outcomes) and demographics Pneumothorax patients treated with N-acetylcysteine ​​and bromhexine When: About a year To whom: Public Conditions: Detailed study information can be made available to interested researchers Treat patients Where to obtain: Author responsible for the study How to obtain: Competent and enthusiastic researchers can document the data after publication Work of the responsible author by providing academic information and self-identification To receive Comments:
public Hossein Rezaei
Bam - Persian Gulf Highway - University Campus
Bam Iran (Islamic Republic of) 7661771967 +98 34 4421 9074 Hossein.rezaei.aliabadi@gmail.com Bam University of Medical Sciences scientific Mojtaba Khojandi
Bam - Persian Gulf Highway - University Campus
Bam Iran (Islamic Republic of) 7661771967 +98 34 4421 9074 Mojtabakhojandi@gmail.com Bam University of Medical Sciences Iran (Islamic Republic of) Patient admitted to the surgical ward Satisfaction with participation in the study Patients with traumatic pneumothorax to a significant extent no limit no limit Both Patients with chronic obstrucrive pulmonary disease ( copd ) Asthma cystic fibrosis bronchitis bronchiectasis AIDS Patients who have undergone intubation Treatment - Drugs Treatment - Drugs Intervention group: In this group, pneumothorax patients are treated orally for one week by implanting chest tube and taking bromhexine tablets, a product of Aveh Sina Pharmaceutical Company, at a dose of 8 mg once a day. Then the patient is photographed chest and in case of recovery of pneumothorax, the time required for chest tube exit is recorded and examined Intervention group: In this group, pneumothorax patients are treated by chest tube implantation and N-acetylcysteine, a product of Aveh Sina Pharmaceutical Company, at a dose of 600 mg as a solution in 30cc of water, every 12 hours orally for one week. Take. Then the patient is photographed chest and in case of recovery of pneumothorax, the time required for chest tube exit is recorded and examined Normalization of symptoms in chest xray. Timepoint: About a week after starting treatment. Method of measurement: Counting the number of days hospitalized. Bam University of Medical Sciences Approved 2022-05-18 Ethics Committee of Bam University of Medical Sciences Bam - Sardaran Shahid Square - Shahid Rajaei Boulevard Bam Kerman Iran (Islamic Republic of)