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IRCT20220603055066N1 IRCT 2022-09-28 Bam University of Medical Sciences Comparative evaluation of PRP with nutritional supplements in improvement of hair loss in patients recovered from COVID-19 Comparative evaluation of PRP (Platelet-Rich Plasma) with nutritional supplements in improvement of hair loss (telogen effluvium) in patients recovered from COVID-19 in Bam Pasteur hospital in 2022 2022-10-02 anticipated 60 Complete https://irct.ir/trial/63995 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment. N/A telogen effluvium. Intervention 1: Therapeutic intervention in the first group includes nutritional supplements (folic acid, vitamin D, zincplus and hair vit.) which are prescribed to the person daily for three months based on daily needs and BMI. Intervention 2: The therapeutic intervention in the second group includes PRP injection once every three weeks and for four sessions. It should be noted that PRP is used autologously and from the patient's own blood product, and the obtained PRP is used only for the patient himself. In this way, 20 ml of the person's venous blood is introduced by a trained nurse in a tube containing sodium citrate and centrifuged for five minutes at a speed of 1500 rpm. Using a sterile syringe, the plasma is transferred to a tube without anticoagulants by a trained nurse and placed in a second centrifuge at 2500 rpm for 20 minutes.The resulting PRP is then collected. Each time PRP is injected intradermally at a dose of 0.1-0.2 ml per injection at a distance of about one centimeter in the interfollicular areas of the frontal and vertebral region by a dermatologist. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.
public Sahar ebrahimi
No. 27, Alley 3, Seyed Al-Shohada Boulevard
Bam Iran (Islamic Republic of) 7661777997 +98 34 4431 1921 faezebahadornia@gmail.com Bam University of Medical Sciences scientific Sahar ebrahimi
No. 27, Alley 3, Seyed Al-Shohada Boulevard
Bam Iran (Islamic Republic of) 7661777997 +98 34 4431 1921 faezabahadornia@gmail.com Bam University of Medical Sciences Iran (Islamic Republic of) Age 20 to 50 years Covid 19 disease (positive by PCR test) 2 to 4 months before enrollment Occurrence of persistent and significant hair loss after Covid 19 disease, which according to the diagnosis of a dermatologist has a pattern similar to telogen effluvium 20 years 50 years Both People who are diagnosed as the other types of alopecia (except telogen effluvium) Pregnant or lactating women Patients who are being treated with drugs such as finasteride, spironolactone, minoxidil or OCP or who have recently stopped taking these drugs Patients who have an underlying disease affecting hair loss Lack of informed consent to enter the study L65.0 Telogen effluvium Treatment - Drugs Treatment - Drugs Therapeutic intervention in the first group includes nutritional supplements (folic acid, vitamin D, zincplus and hair vit.) which are prescribed to the person daily for three months based on daily needs and BMI. The therapeutic intervention in the second group includes PRP injection once every three weeks and for four sessions. It should be noted that PRP is used autologously and from the patient's own blood product, and the obtained PRP is used only for the patient himself. In this way, 20 ml of the person's venous blood is introduced by a trained nurse in a tube containing sodium citrate and centrifuged for five minutes at a speed of 1500 rpm. Using a sterile syringe, the plasma is transferred to a tube without anticoagulants by a trained nurse and placed in a second centrifuge at 2500 rpm for 20 minutes.The resulting PRP is then collected. Each time PRP is injected intradermally at a dose of 0.1-0.2 ml per injection at a distance of about one centimeter in the interfollicular areas of the frontal and vertebral region by a dermatologist. The amount of hair loss. Timepoint: The beginning of the study , 21 , 42 , 63. Method of measurement: Hair pull test. The level of satisfaction of the state of hair loss, increased hair growth and hair quality. Timepoint: The beginning of the study , 21 , 42 , 63. Method of measurement: The satisfaction questionnaire is based on the examination of hair loss before and after the intervention, as well as the satisfaction level regarding the state of hair loss, increased hair growth and hair quality based on a five-point scale from very dissatisfied, which means a score of 0, to very satisfied, which means a score of 5. . Bam University of Medical Sciences Approved 2022-05-20 ethics committee of Bam university of medical sciences No.27, Alley 3, Saiyid ush shohada Blvd Bam Kerman Iran (Islamic Republic of)