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IRCT20220528055004N1 IRCT 2022-07-21 Esfahan University of Medical Sciences Effect of Dexamethasone Mouthwash in Oral Mucositis Evaluation of the Effectiveness of Mouthwash "Soluble Dexamethasone in AlMg Syrup" in Radiotherapy and Chemotherapy-induced Oral Mucositis in Cancer Patients 2022-06-22 anticipated 80 Complete https://irct.ir/trial/64468 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Simple Randomization, Flip the Coin.Based on this, each patient will be placed in one of the two groups after a coin flip.In this way, if the result of flipping a coin is heads, they are included in the control group, and if it is tails they are included in the mouthwash group. 3 Oral mucositis. Intervention 1: Intervention group: Dexamethasone Mouthwash group, In order to keep Dexamethasone on the wounds, it was given to the patients as a solution in AlMg syrup(4 ampoules of Dexa in a bottle of syrup). The patients should rinse their mouths every 8 h, after meals,for 30s with 10 ml(A tablespoon) from mouthwash and  avoid eating and drinking for half an hour. Intervention 2: Control group:There is no intervention in this group and during their treatment in the hospital, they are followed  and monitored for their oral mucositis. Yes - There is a plan to make this available What will be shared: All data and study documentation, such as non-identifiable data and the outcome of interventions, work methods and ... are collected in the form of thesis.In Shahrivar 1401, this information will be presented during a lecture and then it sent to scientific journals for public use When: The beginning of the access period is from 1402 To whom: This information will be accessible to all interested parties. Conditions: 1) In order to increase awareness and improve approaches related to treatment and prevention in the field of research 2)To be presented to medical centers and used in treatment protocols 3)For use in research studies Where to obtain: 1)Dentistry library of the Isfahan University of Medical Sciences, persian theses section, to the website: http://elib.mui.ac.ir/faces/search 2) Send email to: leily.er@gmail.com salehi@dnt.mui.ac.ir 3)Search in scientific databases How to obtain: Search title in the scientific databases and the said site or send email to the email addresses and request Comments:
public Mohammad reza Salehi
No. 10,Dorsa apartment, Mozhgan deadlock, Tabibe esfahani Ave
Isfahan Iran (Islamic Republic of) 8175494055 +98 31 3630 2913 salehi@dnt.mui.ac.ir Esfahan University of Medical Sciences scientific Mohammad reza Salehi
No. 10,Dorsa apartment, Mozhgan deadlock, Tabibe esfahani Ave
Isfahan Iran (Islamic Republic of) 8175494055 +98 31 3630 2913 salehi@dnt.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) People undergoing Chemotherapy or Radiotherapy for Cancer They have Oral Mucositis as a Result of Treatment Complications There are three to four Weeks left in their Treatment no limit no limit Both Patient dissatisfaction Patient non-cooperation K12.31 Oral mucositis (ulcerative) due to antineoplastic therapy Treatment - Other N/A Intervention group: Dexamethasone Mouthwash group, In order to keep Dexamethasone on the wounds, it was given to the patients as a solution in AlMg syrup(4 ampoules of Dexa in a bottle of syrup). The patients should rinse their mouths every 8 h, after meals,for 30s with 10 ml(A tablespoon) from mouthwash and  avoid eating and drinking for half an hour Control group:There is no intervention in this group and during their treatment in the hospital, they are followed  and monitored for their oral mucositis Grade of mucositis. Timepoint: The beginning of the study(Before intervention),7,14and 21 days after the starting. Method of measurement: In-person examination and registration based on World Health Organization's mucositis grading scale and Visual Analogue Scale. Esfahan University of Medical Sciences Approved 2022-05-16 Ethics committee of Isfahan University of Medical Sciences No. 34 , Block c , Zayanderud building , In front of Najvan entrance , Sohrvardi square Isfahan Isfehan Iran (Islamic Republic of)