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IRCT20220702055347N1 IRCT 2023-06-20 Tarbiat Modares University of Tehran The Effect of a Multi Component Exercise Program on Cognitive Function of Women with Type 2 Diabetes The Effect of a Multi Component Exercise Program on Cognitive Function in Women with Type 2 Diabetes, with a Special Focus on Serum Levels and Geno typing of Selected cytokine TNF alpha and IL-10 Polymorphisms 2023-06-22 anticipated 100 Complete https://irct.ir/trial/64586 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Education/Guidance, Randomization description: The samples will be determined by the random block method with blocks of 4 and using the random number table of the random allocation software. Blocking and allocation sequence will be done for concealment by a person not involved in the research (allocation concealment). The allocation ratio of the samples will be one to one and they will be placed in two sports intervention and control groups. Then, based on the obtained blocks and according to the allocation sequence, the multiple exercise training program will be given to the exercise intervention group. Blinding will not occur in this study. N/A Type 2 Diabetes. Intervention 1: "Intervention group": A 3-month multi component exercise intervention consisting of stretching, resistance, dual task and balance exercises will be implemented. The intensity of aerobic exercises will be kept 40 to 60 maximum reserve heart rate and the number of sessions will increase from 3 to 5 per week. Intervention 2: "Control group":No intervention will be carried out in this group, and patients will continue their usual routine before the pre-test. Yes - There is a plan to make this available What will be shared: Part of the data related to the main outcome can be shared. When: The access period starts 6 months after the results are published. To whom: People approved by the supervisor Conditions: For scientific purposes Where to obtain: Supervisor How to obtain: E-mail correspondence with the supervisor molanouri@modares.ac.ir Comments:
public Dr.Mahdieh Molanouri Shamsi
Nasr Bridge,Jalal Al Ahmad St,Tehran,Iran
Tehran Iran (Islamic Republic of) 1411713116 +98 21 8288 4683 molanouri@modares.ac.ir Tarbiat Modares University of Tehran scientific Mahdie Molanori Shamsi
Nasr Bridge,Jalal Al Ahmad St,Tehran,Iran
Tehran Iran (Islamic Republic of) 1411713116 +98 21 8288 0000 molanouri@modares.ac.ir Tarbiat Modares University of Tehran Iran (Islamic Republic of) Iran (Islamic Republic of) Fasting blood glucose more than 7 mmol/L Hemoglobin A1c more than 6.5 Do not have cognitive function, heart and joint problems People with type 2 diabetes Be in the desired age range 50 years 75 years Female E11.9 Type 2 diabetes mellitus without complications Lifestyle Lifestyle "Intervention group": A 3-month multi component exercise intervention consisting of stretching, resistance, dual task and balance exercises will be implemented. The intensity of aerobic exercises will be kept 40 to 60 maximum reserve heart rate and the number of sessions will increase from 3 to 5 per week. "Control group":No intervention will be carried out in this group, and patients will continue their usual routine before the pre-test. Interleukin 10 genotyping. Timepoint: Before and after 3 months interventions. Method of measurement: Restriction fragment length polymorphism. Tumour necrosis factor α genotyping. Timepoint: Before and after 3 months interventions. Method of measurement: Restriction fragment length polymorphism. Tumor necrosis factor alpha cytokine. Timepoint: Before and after 3 months intervention. Method of measurement: Enzyme-linked immunosorbent assay. Interleukin 10 cytokine. Timepoint: Before and after 3 months intervention. Method of measurement: Enzyme-linked immunosorbent assay. Executive function. Timepoint: Before and after 3 months intervention. Method of measurement: Trail Making Test. Respiratory and cardiovascular system, blood circulation and muscle. Timepoint: Before and after 3 months intervention. Method of measurement: 6-Minute Walk Test. Body Mass Index. Timepoint: Before and after 3 months intervention. Method of measurement: Weight in kilograms divided by the square of height in meters. Cognitive Sciences and Technology Council Tarbiat Modares University of Tehran Cognitive Sciences and Technology Council Approved 2022-01-22 Ethics Committee of Tarbiat Modares University Jalal Al Ahmad St Tehran Tehran Iran (Islamic Republic of)