IRCT20220713055465N1 IRCT 2022-08-30 Tabriz University of Medical Sciences Probiotic supplementation in multiple sclerosis The effects of probiotics in functional abilities of multiple sclerosis patients: a randomized double-blind placebo-control trial 2022-08-23 anticipated 90 Complete https://irct.ir/trial/64785 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Table of random numbers In this method, each person participating in the study is assigned a number (from 1 to 90; according to the sample size) and a subset of the population is randomly selected using a table of random numbers. Even numbers are assigned to the intervention group and odd numbers to the placebo group, Blinding description: The examiner, the patient, and the data analyst will not know the type of intervention the patient received. 2 Multiple Sclerosis. Intervention 1: Intervention group: LactoCare probiotic supplement that contains high amounts of 12 beneficial and safe bacterial strains along with fructooligosaccharides as prebiotics. Patients will take this supplement once daily and oral for 4 months. Intervention 2: Control group: placebo. This capsule contains an ineffective substance (starch powder) that patients will take once daily for 4 months. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information