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IRCT20220717055482N1 IRCT 2023-06-18 Tabriz University of Medical Sciences effect of the mouthwash containing propolis-aloe vera plant Comparative effect of the mouthwash containing propolis-aloe vera plant extract and chlorhexidine solution on plaque and gingival bleeding indexes in Generalized marginal gingivitis patients. 2022-12-11 anticipated 60 Complete https://irct.ir/trial/64794 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, the permutation block method will be used to randomly assign patients to the studied treatment groups. For this purpose, 20 blocks of three will be created including the studied treatments, in each block a random sequence of A, B, C will be created. The blocks will be randomly selected and based on the sequence in each group of patients, they will be assigned to 3 treatment groups from the beginning of the list of patients. To create a random sequence, a table of random numbers will be used. 3 gingivitis. Intervention 1: Control group: They receive distilled water,. Patients are asked to rinse their mouth twice a day with the mouthwash they have for 14 days. Intervention 2: Intervention group 1 :BEHSA Chlorhexidine 0.2%. Patients are asked to rinse their mouth twice a day each turn 10 ml with the mouthwash they have for 14 days. Intervention 3: Intervention group 2: Aloevera propolis 50% water base (formulated in Tabriz Faculty of Pharmacy) , patients are taught to use 10 cc of the related mouthwash twice a day for two weeks after brushing their teeth, and after 1 minute, they should pour the mouthwash out of their mouth and avoid eating and drinking for half an hour, the patients are then called after the end of the second week and the gingival index, plaque index and bleeding during probing are recorded. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is I haven't decided yet and I don't know the best way to publish
public Sayna Jahed
No 16.,Golbad Ave.,Valiasr St.,Tabriz Town
Tabriz Iran (Islamic Republic of) 5157686977 +98 41 3328 0495 saynaja@yahoo.com Tabriz University of Medical Sciences scientific Sayna Jahed
No 16.,Golbad Ave.,Valiasr St.,Tabriz Town
Tabriz Iran (Islamic Republic of) 5157686977 +98 41 3328 0495 saynaja@yahoo.com Tabriz University of Medical Sciences Iran (Islamic Republic of) patients with Generalized marginal gingivitis Have not received antibiotics in the last 6 months. Not in puberty or pregnant Do not have systemic diseases that cause generalized gingivitis. patients which not committed to periodontitis no limit no limit Both Patients with cardiovascular diseases and diabetes People who smoke. Patients with chronic or acute infections. uncontrolled diabetics K05.1 Chronic gingivitis Placebo Treatment - Drugs Treatment - Drugs Control group: They receive distilled water,. Patients are asked to rinse their mouth twice a day with the mouthwash they have for 14 days. Intervention group 1 :BEHSA Chlorhexidine 0.2%. Patients are asked to rinse their mouth twice a day each turn 10 ml with the mouthwash they have for 14 days. Intervention group 2: Aloevera propolis 50% water base (formulated in Tabriz Faculty of Pharmacy) , patients are taught to use 10 cc of the related mouthwash twice a day for two weeks after brushing their teeth, and after 1 minute, they should pour the mouthwash out of their mouth and avoid eating and drinking for half an hour, the patients are then called after the end of the second week and the gingival index, plaque index and bleeding during probing are recorded. Plaque index in probing. Timepoint: before intervention and 2 weeks after intervention. Method of measurement: inclusive tablet ,Williams probe. Bleeding in probing. Timepoint: before intervention and 2 weeks after intervention. Method of measurement: inclusive tablet ,Williams probe. Depth of envelope in probing. Timepoint: before intervention and 2 weeks after intervention. Method of measurement: inclusive tablet ,Williams probe. Tabriz university of medical science Approved 2022-06-27 Ethics committee of Tabriz university of medical sciences Research and Technology Vice-Chancellor 3rd Floor ,Central Building No 2 ,Tabriz University of Medical Sciences , Golgasht Street ,Tabriz Tabriz East Azarbaijan Iran (Islamic Republic of)