]>
IRCT20210118050067N2 IRCT 2022-08-19 Esfahan University of Medical Sciences Comparison of buccal patches containing lidocaine and dexmedetomidine with articaine and dexmedetomidine in dental procedures Preparation and comparison of buccal patches containing lidocaine and dexmedetomidine with articaine and dexmedetomidine in reduction of injection pain and increment of patients compliance in dental procedures 2022-08-23 anticipated 180 Complete https://irct.ir/trial/64892 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: We use the random number table method. Each patient is assigned a number, and based on the random number table, an envelope is considered for each patient. On the envelope, the name, surname, number associated with that patient and the patch are placed inside. This envelope is opened by the project manager (neither the patient nor the dentist can see the contents of the envelope). Then the dentist apply the patch to the patient and after its effect, dentist perform the injection, Blinding description: In the randomization description section, we explained about the envelope related to the patient and its contents. This envelope is opened by the project manager (neither the patient nor the dentist can see the contents of the envelope). 2 Pain caused by local anesthetic injection.. Intervention 1: Intervention group: Patients in this group receive a patch containing 350 mg of lidocaine. Intervention 2: Intervention group: Patients in this group receive a patch containing 350 mg of articaine. Intervention 3: Intervention group: Patients in this group receive a patch containing 350 mg of lidocaine + 1 microgram of dexmedetomidine per kilogram. Intervention 4: Intervention group: Patients in this group receive a patch containing 350 mg articaine + 1 microgram per kilogram of dexmedetomidine. Intervention 5: Control group: Patients in this group receive a drug-free patch. Intervention 6: Control group: Patients in this group receive only injectable lidocaine. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.
public Milad Etemadi
Al-Zahra hospital, Soffe Blvd, Keshvari Expy, Isfahan
Isfahan Iran (Islamic Republic of) 8174675731 +98 31 3792 5581 etemadi@dnt.mui.ac.ir Esfahan University of Medical Sciences scientific Milad Etemadi
Al-Zahra hospital, Soffe Blvd, Keshvari Expy, Isfahan
Isfahan Iran (Islamic Republic of) 8174675731 +98 31 3792 5581 etemadi@dnt.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) Patients should cooperate for the study. Visiting for dental services that require local anesthesia. 20 years 35 years Both Those with any systemic disease (cardiovascular disease, diabetes, etc.), physical and mental illness. Patients who have a history of taking any painkillers and corticosteroids in the last week. Patients who have allergy to lidocaine and articaine. Patients who have dental phobia. Patients who have inflammation, abscess, and history of surgery at the injection site. Z98818 Other dental procedure status Treatment - Drugs Treatment - Drugs Treatment - Drugs Treatment - Drugs Treatment - Drugs Treatment - Drugs Intervention group: Patients in this group receive a patch containing 350 mg of lidocaine. Intervention group: Patients in this group receive a patch containing 350 mg of articaine. Intervention group: Patients in this group receive a patch containing 350 mg of lidocaine + 1 microgram of dexmedetomidine per kilogram. Intervention group: Patients in this group receive a patch containing 350 mg articaine + 1 microgram per kilogram of dexmedetomidine. Control group: Patients in this group receive a drug-free patch. Control group: Patients in this group receive only injectable lidocaine. Pain caused by injection. Timepoint: 20 minutes after lidocaine injection. Method of measurement: After finishing the procedure, we ask the patients to mark the pain they experienced on the Visual Analogue Scale from 0 to 10. Esfahan University of Medical Sciences Approved 2022-06-22 Ethics committee of Isfahan University of Medical Sciences Faculty of pharmacy , Isfahan university of medical sciences, Hezarjarib St , Isfahan Isfahan Isfehan Iran (Islamic Republic of)