]>
IRCT20220719055496N1 IRCT 2022-07-26 Esfahan University of Medical Sciences Investigating the effect of adding Transcranial direct current stimulation (TDCS) to acetaminophen codeine in reducing pain in cancer patients Investigating the effect of adding Transcranial direct current stimulation (TDCS) to acetaminophen codeine in reducing the pain of cancer patients in Isfahan city in 1401 2022-08-06 anticipated 30 Complete https://irct.ir/trial/64919 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: After entering, patients will be divided into two groups by random allocation software in individual units by simple randomization method. After that, one of the groups will be randomly assigned to the intervention group and the other group to the control group, Blinding description: The patients included in the study and the health care workers do not know the type of intervention performed (TDCS or not) in the study. 3 cancer related pain. Intervention 1: Intervention group: The pain score of patients in this group is measured at the beginning of the study. Then the patients were treated for pain control with acetaminophen codeine along with Transcranial direct current stimulation (TDCS, with two electrodes that are placed on both sides of the head and then a current of 2 mA passes between them for 20 minutes) for 4 consecutive days in They are placed 4 separate times. After that, in the first week after the intervention, in the second, third and fourth week, the pain score of the patients is again measured by VAS (Visual Analog Scale) ruler. Intervention 2: Control group: The pain score of these patients is measured at the beginning of the study. Then the patients are treated with acetaminophen codeine alone for 4 consecutive days and for 4 separate times. Also, TDCS electrodes are placed on their heads, but no current passes through them. Then the pain of the patients is measured in the first week after the intervention, the second week, the third week and the fourth week by VAS (Visual Analog Scale) ruler. Yes - There is a plan to make this available What will be shared: All data collected from patients can be shared after de-identification When: Access starts for one year after the results are published To whom: Doctors, researchers Conditions: The data will be used to conduct further studies in order to improve the condition of patients Where to obtain: Dr. Dorsa Davoodpour How to obtain: After sending an email to receive data and verify identity, verify the person's job and the use of the data, the request will be reviewed and if approved, the data will be sent. Comments:
public Dorsa Davoodpour
No. 2, Midas Building, Shahid Alikhani Ave, Shahid Karimian Ave, Baghdaryache St
Esfahan Iran (Islamic Republic of) 8176755967 +98 31 3786 2350 Dorsa.davoodpour@gmail.com Esfahan University of Medical Sciences scientific Dorsa Davoodpour
No. 2, Midas Building, Shahid Alikhani Ave, Shahid Karimian Ave, Baghdaryache St
Esfahan Iran (Islamic Republic of) 8176755967 +98 31 3786 2350 Dorsa.davoodpour@gmail.com Esfahan University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Any type of cancer Suffering from moderate to severe pain caused by cancer based on VAS score (5-10) Informed consent to participate in the study Absence of depressive disorders, bipolar disorders, or psychotic disorders based on DSM-V diagnostic criteria during examination by a psychiatrist and a psychiatric assistant No history of epilepsy and other neurological disorders Absence of pregnancy No addiction to drugs and opium Not having implants in the skull or pacemakers or any other prosthetics No prior exposure to transcranial stimulation treatments 18 years 65 years Both The final stage of cancer Lack of informed consent Aggravation of cancer symptoms and the need for hospitalization during the study Intensification of pain in such a way that it is necessary to prescribe strong narcotics (morphine, methadone, oxycodone, pethidine) G89.3 Neoplasm related pain (acute) (chronic) Other Other Intervention group: The pain score of patients in this group is measured at the beginning of the study. Then the patients were treated for pain control with acetaminophen codeine along with Transcranial direct current stimulation (TDCS, with two electrodes that are placed on both sides of the head and then a current of 2 mA passes between them for 20 minutes) for 4 consecutive days in They are placed 4 separate times. After that, in the first week after the intervention, in the second, third and fourth week, the pain score of the patients is again measured by VAS (Visual Analog Scale) ruler Control group: The pain score of these patients is measured at the beginning of the study. Then the patients are treated with acetaminophen codeine alone for 4 consecutive days and for 4 separate times. Also, TDCS electrodes are placed on their heads, but no current passes through them. Then the pain of the patients is measured in the first week after the intervention, the second week, the third week and the fourth week by VAS (Visual Analog Scale) ruler Pain score of cancer patients according to VAS (Visual Analog Scale). Timepoint: before the intervention and one week, two weeks, three weeks and four weeks after the intervention. Method of measurement: The pain score of the patients is measured by the Visual Analog Scale ruler. Esfahan University of Medical Sciences Approved 2022-04-28 Ethics committee of Isfahan University of Medical Sciences Isfahan university of Medical Science, Hezar Jarib St Isfahan Isfehan Iran (Islamic Republic of)