IRCT20220809055644N1 IRCT 2022-10-12 Rasht University of Medical Sciences "Efficacy of diuretic therapy with furosemide compared with combined diuretic therapy with furosemide and indapamide in treatment of congestive heart failure" Evaluation the efficacy of diuretic therapy with furosemide compared with combined diuretic therapy with furosemide and indapamide in treatment of patients with congestive heart failure: A randomized clinical trial 2022-08-23 anticipated 180 Complete https://irct.ir/trial/65180 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The website http://www.randomization.com/ will be used for randomization. The randomization of this study will be by the blocked randomization method. Based on the list of codes obtained from this website, each patient will be randomly assigned to the intervention or control group using blocks of 4 in a ratio of 1:1. For concealment, a code will be assigned to each patient and each of the randomly generated codes will be written on a card. Then they will be placed inside sealed opaque envelopes in random order. In order to maintain the random sequence, the outer surface of the envelopes will be numbered in the same order. Finally, the lid of the letter envelopes will be glued and will be placed in a box respectively. At the time of sampling, one of the envelopes will be determined according to the opening order and the assigned group of that participant, Blinding description: For the purpose of blinding, placebos completely identical in terms of color, smell, shape and size to indapamide drug will be prepared for this study. The indapamide drug used for the patients of this plan will also be provided to the patients without any label (only if it is obvious to the person giving the medicine) in unlabeled cans and by the prescribing doctor. In this study, participants and Assessors are blind. 2-3 Congestive heart failure. Intervention 1: Intervention group: It will include 90 patients with congestive heart failure. In addition to the daily consumption of furosemide 20 mg three times a day, one pill each time, the intervention group will also take the diuretic indapamide 1.5 mg once a day. This group will take furosemide and indapamide diuretics for three months. Intervention 2: Control group: Control group: Including 90 patients with congestive heart failure. For the participants in the control group, the diuretic furosemide will be prescribed along with placebo. In this way, the patients of this group will take furosemide 20 mg three times a day, one tablet each time, and placebo one tablet a day. This group will take furosemide and placebo for three months. No - There is not a plan to make this available Justification or reason for not sharing IPD is "No more information"