IRCT20220817055729N1 IRCT 2023-01-17 Oroumia University of Medical Sciences doxium and retinopathy in diabetic patients Evaluation of the effect of doxium on vision and macular thickness in patients with mild to moderate diabetic retinopathy 2022-09-23 anticipated 40 Complete https://irct.ir/trial/65314 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The samples of the participants in the study were randomly divided into two intervention and control groups using computer randomization software. The way of randomization in the groups will be that each patient is given a code and the codes are entered Microsoft Excel 2010 software and by executing the Randomization command and defining two groups, the software randomly places the codes in two separate groups. Then the output codes of the software will be placed in two groups 1 (intervention) and 2 (placebo), Blinding description: Each eye was randomly assigned to receive one group of the medication. All preparations were individually prepared for each patient and patients and investigators were kept blinded to the randomized allocation and details of series of the medications throughout the study. 2-3 Diabetic retinopathy. Intervention 1: 50 mg of oral capsule doxium (Om Pharma, Switzerland) once a days for 180 days (maximum duration of intervention is 180 days). Intervention 2: Control group: simulating placebo capsule for 6 months. Yes - There is a plan to make this available What will be shared: The study aim will be described to all participants When: Hospital authorities for 1 year To whom: Hospital authorities Conditions: Formal written permission form from the hospital Where to obtain: Online via corresponding author email How to obtain: Taking formal permision form from hospital with hospital authorities signature should be sent to corresponding author Comments: