IRCT20141001019359N14 IRCT 2022-09-28 Bojnourd University of Medical Sciences Comparison of the effect of Dexmedetomidine with intravenous Paracetamol on Pain induced by Propofol Comparison of the effect of Dexmedetomidine with intravenous Paracetamol on Pain induced by Propofol 4oc injection; A double-Blind Randomized Clinical Trial 2022-10-07 anticipated 90 Complete https://irct.ir/trial/65748 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Sampling in this study will be that first in order to enter the study patients will be in the form of non-random sampling of the type "available" and then divide them into three groups by randomly assigned blocking using a web-based system. Random blocking at www.randomization.com will be done in 15 blocks of 6. So that in each block, there are 2 people in the first group (A), two people in the second group (B) and two people in the third group (C). After a random sequence was identified in all blocks, cards were written by writing C, B, and A to indicate which group each patient was assigned to, and by someone other than the research team from 1 to 90 in all blocks, respectively. They are numbered and these cards are placed in sealed non-transparent envelopes, respectively. Then, in order to hide the random allocation, when the patient visits, the opaque sealed envelope will be opened and then one by one, it will be determined for each sample of the relevant group, Blinding description: None of the participants in the study will be aware of the randomization list, and in order to conceal the randomization process, the groups will be placed in closed envelopes in the reception area and will be assigned to the eligible individuals who enter the study. Also, in order to blind the patients to the study groups, all patients will receive the desired drugs intravenously and In order to blind the anesthetist nurse (who is responsible for injecting drugs intravenously for patients), the arms of all patients will be covered with a cloth. 3 Pain. Intervention 1: Intervention group A: Before induction of anesthesia, Dexmedetomidine (0.5 µg/kg) will be slowly injected for 5 minutes. Intervention 2: Intervention group B: Before induction of anesthesia, Paracetamol (2 mg/kg) will be slowly injected for 5 minutes. Intervention 3: Control group: Before induction of anesthesia 40 mg of Lidocaine is dissolved in a 10 cc syringe and will be slowly injected to the patient over a period of 3 minutes. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information.